Literature DB >> 33547810

Concurrent chronic hyperplastic candidosis and oral lichenoid lesion as adverse events of secukinumab therapy.

C S Farah1,2,3.   

Abstract

Secukinumab (Cosentyx®) is an IL-17A inhibitor which is used for the management of psoriasis, active psoriatic arthritis or ankylosing spondylitis. Oral adverse events of secukinumab therapy are not widely appreciated. This article highlights the presentation of two concurrent oral adverse events of secukinumab therapy; namely chronic hyperplastic candidosis (CHC) and oral lichenoid lesion (OLL). This is the first documented case report of CHC occurring as a consequence of secukinumab therapy, and represents a new adverse effect which general and specialist oral health practitioners should be aware of. This case highlights the importance of correlating the presence of oral lesions with the patient's medical history, keeping up to date with the development of new medications and pharmacotherapeutics, having a deep understanding of underlying biological processes related to various oral diseases, and appreciating the use of clinical adjunctive devices. Accurate diagnosis is key to formulating a correct management plan.
© 2021 Australian Dental Association.

Entities:  

Keywords:  IL-17 inhibitor; chronic hyperplastic candidosis; oral adverse event; oral lichenoid lesion; secukinumab

Year:  2021        PMID: 33547810     DOI: 10.1111/adj.12833

Source DB:  PubMed          Journal:  Aust Dent J        ISSN: 0045-0421            Impact factor:   2.291


  2 in total

1.  Atypical oral candidiasis in a psoriatic patient during targeted immunotherapy with an interleukin 17 inhibitor (secukinumab).

Authors:  Bruna Lavinas Sayed Picciani; Arkadiusz Dziedzic; Juliana Tristão Werneck; Marcello Alves Marinho; Thaylla Núñez Amin Dick; Nara Regina Quintanilha; Eliane Pedra Dias
Journal:  BMC Oral Health       Date:  2021-06-08       Impact factor: 2.757

2.  Oral Candida Infection in Psoriatic Patients Treated with IL17A Inhibitors: Report of 3 Cases and a Comprehensive Review of the Literature.

Authors:  Efstathios Pettas; Vasiliki Savva; Vasileios Ionas Theofilou; Maria Georgaki; Nikolaos G Nikitakis
Journal:  Diagnostics (Basel)       Date:  2021-12-21
  2 in total

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