Literature DB >> 33546347

COVID-19 Vaccination: From Interesting Agent to the Patient.

Anis Daou1,2.   

Abstract

The vaccination for the novel Coronavirus (COVID-19) is undergoing its final stages of analysis and testing. It is an impressive feat under the circumstances that we are on the verge of a potential breakthrough vaccination. This will help reduce the stress for millions of people around the globe, helping to restore worldwide normalcy. In this review, the analysis looks into how the new branch of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) came into the forefront of the world like a pandemic. This review will break down the details of what COVID-19 is, the viral family it belongs to and its background of how this family of viruses alters bodily functions by attacking vital human respiratory organs, the circulatory system, the central nervous system and the gastrointestinal tract. This review also looks at the process a new drug analogue undergoes, from (i) being a promising lead compound to (ii) being released into the market, from the drug development and discovery stage right through to FDA approval and aftermarket research. This review also addresses viable reasoning as to why the SARS-CoV-2 vaccine may have taken much less time than normal in order for it to be released for use.

Entities:  

Keywords:  COVID-19; drug development and discovery; pandemic; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); vaccination

Year:  2021        PMID: 33546347      PMCID: PMC7913564          DOI: 10.3390/vaccines9020120

Source DB:  PubMed          Journal:  Vaccines (Basel)        ISSN: 2076-393X


  57 in total

Review 1.  Target discovery.

Authors:  Mark A Lindsay
Journal:  Nat Rev Drug Discov       Date:  2003-10       Impact factor: 84.694

2.  A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.

Authors:  Karuppiah Muthumani; Darryl Falzarano; Emma L Reuschel; Colleen Tingey; Seleeke Flingai; Daniel O Villarreal; Megan Wise; Ami Patel; Abdullah Izmirly; Abdulelah Aljuaid; Alecia M Seliga; Geoff Soule; Matthew Morrow; Kimberly A Kraynyak; Amir S Khan; Dana P Scott; Friederike Feldmann; Rachel LaCasse; Kimberly Meade-White; Atsushi Okumura; Kenneth E Ugen; Niranjan Y Sardesai; J Joseph Kim; Gary Kobinger; Heinz Feldmann; David B Weiner
Journal:  Sci Transl Med       Date:  2015-08-19       Impact factor: 17.956

3.  B-cell responses in patients who have recovered from severe acute respiratory syndrome target a dominant site in the S2 domain of the surface spike glycoprotein.

Authors:  Xiaofen Zhong; Huanghao Yang; Zu-Feng Guo; Wan-Yee Fion Sin; Wei Chen; Junjie Xu; Ling Fu; Jie Wu; Chun-Kit Gannon Mak; Chak-Sum Samuel Cheng; Yanzhen Yang; Shuyong Cao; Tin-Yau Wong; Sik-To Lai; Yong Xie; Zhihong Guo
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

4.  Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice.

Authors:  Himani Bisht; Anjeanette Roberts; Leatrice Vogel; Alexander Bukreyev; Peter L Collins; Brian R Murphy; Kanta Subbarao; Bernard Moss
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-19       Impact factor: 11.205

5.  Safety and immunogenicity of an adjuvanted herpes zoster subunit candidate vaccine in HIV-infected adults: a phase 1/2a randomized, placebo-controlled study.

Authors:  Elchonon M Berkowitz; Graeme Moyle; Hans-Jürgen Stellbrink; Dirk Schürmann; Stephen Kegg; Matthias Stoll; Mohamed El Idrissi; Lidia Oostvogels; Thomas C Heineman
Journal:  J Infect Dis       Date:  2014-11-03       Impact factor: 5.226

Review 6.  Vaccines for the prevention against the threat of MERS-CoV.

Authors:  Lanying Du; Wanbo Tai; Yusen Zhou; Shibo Jiang
Journal:  Expert Rev Vaccines       Date:  2016-04-06       Impact factor: 5.217

7.  An mRNA Vaccine against SARS-CoV-2 - Preliminary Report.

Authors:  Lisa A Jackson; Evan J Anderson; Nadine G Rouphael; Paul C Roberts; Mamodikoe Makhene; Rhea N Coler; Michele P McCullough; James D Chappell; Mark R Denison; Laura J Stevens; Andrea J Pruijssers; Adrian McDermott; Britta Flach; Nicole A Doria-Rose; Kizzmekia S Corbett; Kaitlyn M Morabito; Sijy O'Dell; Stephen D Schmidt; Phillip A Swanson; Marcelino Padilla; John R Mascola; Kathleen M Neuzil; Hamilton Bennett; Wellington Sun; Etza Peters; Mat Makowski; Jim Albert; Kaitlyn Cross; Wendy Buchanan; Rhonda Pikaart-Tautges; Julie E Ledgerwood; Barney S Graham; John H Beigel
Journal:  N Engl J Med       Date:  2020-07-14       Impact factor: 91.245

8.  A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice.

Authors:  Zhi-Yong Yang; Wing-Pui Kong; Yue Huang; Anjeanette Roberts; Brian R Murphy; Kanta Subbarao; Gary J Nabel
Journal:  Nature       Date:  2004-04-01       Impact factor: 49.962

9.  A Novel Coronavirus from Patients with Pneumonia in China, 2019.

Authors:  Na Zhu; Dingyu Zhang; Wenling Wang; Xingwang Li; Bo Yang; Jingdong Song; Xiang Zhao; Baoying Huang; Weifeng Shi; Roujian Lu; Peihua Niu; Faxian Zhan; Xuejun Ma; Dayan Wang; Wenbo Xu; Guizhen Wu; George F Gao; Wenjie Tan
Journal:  N Engl J Med       Date:  2020-01-24       Impact factor: 91.245

10.  Challenges and Controversies to Testing for COVID-19.

Authors:  Matthew J Binnicker
Journal:  J Clin Microbiol       Date:  2020-10-21       Impact factor: 5.948

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  3 in total

Review 1.  An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times.

Authors:  Cielo García-Montero; Oscar Fraile-Martínez; Coral Bravo; Diego Torres-Carranza; Lara Sanchez-Trujillo; Ana M Gómez-Lahoz; Luis G Guijarro; Natalio García-Honduvilla; Angel Asúnsolo; Julia Bujan; Jorge Monserrat; Encarnación Serrano; Melchor Álvarez-Mon; Juan A De León-Luis; Miguel A Álvarez-Mon; Miguel A Ortega
Journal:  Vaccines (Basel)       Date:  2021-04-27

2.  Heterologous prime-boost vaccination against COVID-19: is it safe and reliable?

Authors:  Om Prakash Choudhary; Jivan Q Ahmed; Teroj A Mohammed; Indraj Singh; Alfonso J Rodriguez-Morales
Journal:  Hum Vaccin Immunother       Date:  2021-12-13       Impact factor: 3.452

Review 3.  COVID-19: A pluralistic and integrated approach for efficient management of the pandemic.

Authors:  Nouhoum Bouare; Daouda Kassim Minta; Abdoulaye Dabo; Christiane Gerard
Journal:  World J Virol       Date:  2022-01-25
  3 in total

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