Literature DB >> 33546313

Recent Advances in p53.

Gabriella D'Orazi1,2.   

Abstract

Tumor suppressor protein p53 (TP53) is a key transcription factor that, in response to various stress signals, regulates numerous genes involved in a broad range of cellular functions including DNA repair, apoptosis, cell cycle arrest, senescence, metabolism, etc [...].

Entities:  

Year:  2021        PMID： 33546313      PMCID： PMC7913554          DOI： 10.3390/biom11020211

Source DB:  PubMed          Journal:  Biomolecules        ISSN： 2218-273X


  17 in total

1.  MicroRNA: Biogenesis, Function and Role in Cancer.

Authors:  Leigh-Ann Macfarlane; Paul R Murphy
Journal:  Curr Genomics       Date:  2010-11       Impact factor: 2.236

Review 2.  Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

Authors:  Ramona Schulz-Heddergott; Ute M Moll
Journal:  Cancers (Basel)       Date:  2018-06-07       Impact factor: 6.639

Review 3.  Follow the Mutations: Toward Class-Specific, Small-Molecule Reactivation of p53.

Authors:  Stewart N Loh
Journal:  Biomolecules       Date:  2020-02-14

Review 4.  p53's Extended Reach: The Mutant p53 Secretome.

Authors:  Evangelos Pavlakis; Thorsten Stiewe
Journal:  Biomolecules       Date:  2020-02-15

Review 5.  Recent Synthetic Approaches towards Small Molecule Reactivators of p53.

Authors:  Jerson L Silva; Carolina G S Lima; Luciana P Rangel; Giulia D S Ferretti; Fernanda P Pauli; Ruan C B Ribeiro; Thais de B da Silva; Fernando C da Silva; Vitor F Ferreira
Journal:  Biomolecules       Date:  2020-04-20

Review 6.  Mutant p53 and Cellular Stress Pathways: A Criminal Alliance That Promotes Cancer Progression.

Authors:  Gabriella D'Orazi; Mara Cirone
Journal:  Cancers (Basel)       Date:  2019-05-02       Impact factor: 6.639

7.  PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR.

Authors:  Maria Anele Romeo; Maria Saveria Gilardini Montani; Rossella Benedetti; Alessia Garufi; Gabriella D'Orazi; Mara Cirone
Journal:  Biomolecules       Date:  2020-04-10

8.  TP53 Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer.

Authors:  Silvia R Vitale; Floris H Groenendijk; Ronald van Marion; Corine M Beaufort; Jean C Helmijr; Hendrikus Jan Dubbink; Winand N M Dinjens; Patricia C Ewing-Graham; Ramon Smolders; Helena C van Doorn; Ingrid A Boere; Els M J J Berns; Jozien Helleman; Maurice P H M Jansen
Journal:  Biomolecules       Date:  2020-03-07

Review 9.  Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells.

Authors:  Marco Cordani; Giovanna Butera; Raffaella Pacchiana; Francesca Masetto; Nidula Mullappilly; Chiara Riganti; Massimo Donadelli
Journal:  Biomolecules       Date:  2020-02-26

10.  Investigation of a Direct Interaction between miR4749 and the Tumor Suppressor p53 by Fluorescence, FRET and Molecular Modeling.

Authors:  Anna Rita Bizzarri; Salvatore Cannistraro
Journal:  Biomolecules       Date:  2020-02-22
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  2 in total

1.  Prognostic value of p16, p53, and pcna in sarcoma and an evaluation of immune infiltration.

Authors:  Dechao Cai; Xiao Ma; Huihui Guo; Haotian Zhang; Ashuai Bian; Haoran Yu; Wendan Cheng
Journal:  J Orthop Surg Res       Date:  2022-06-10       Impact factor: 2.677

Review 2.  Cross-Talk between p53 and Wnt Signaling in Cancer.

Authors:  Qiyun Xiao; Johannes Werner; Nachiyappan Venkatachalam; Kim E Boonekamp; Matthias P Ebert; Tianzuo Zhan
Journal:  Biomolecules       Date:  2022-03-15
  2 in total

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