Yun Peng1, Xianxian Guo2, Junan Liu2, Yuanyuan Yao1, Hui Guo1, Yuan Wang1, Xuan Xiao3, Lin Ye4. 1. Shenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, China. 2. School of Public Health, Tongji Medical College of Huazhong University of Science Technology, Wuhan, China. 3. Eye Center, Renmin Hospital of Wuhan University, Wuhan, China. Email: xiaoxuan1111@163.com. 4. Shenzhen Eye Hospital, Shenzhen Key Laboratory of Ophthalmology, Affiliated Shenzhen Eye Hospital of Jinan University, Shenzhen, China. Email: yelin0711@126.com.
Abstract
BACKGROUND: To understand the prevalence of diabetic retinopathy (DR) in Shenzhen and to analyze the risk factors for the occurrence and development of DR. Based on the comprehensive information system for diabetes prevention and control in the communities of Shenzhen in 2019, six community health service centers in Shenzhen were used as research sites to carry out multicenter, cross-sectional screening studies. METHODS: Cluster random sampling was used to collect data from 904 patients with diabetes in Shenzhen. The occurrence of DR and vision-threatening diabetic retinopathy (VTDR) was analyzed, and multivariate logistic regression was performed to analyze the risk factors for DR and VTDR. EpiData version 3.1 (EpiData Association, Odense, Denmark) statistical software was used to build a database, and Statistical Package for the Social Sciences (SPSS) version 25.0 (IBM Corp., Armonk, N.Y., USA) was used to sort up and analyze the data. RESULTS: The prevalence of DR among diabetic patients in Shenzhen was 18.58% [95% confidence interval (CI): 16.13-21.3%], and the prevalence of VTDR was 2.43% (95% CI: 1.57-1.2%). The prevalence of DR and VTDR was higher in males than in females. Logistic regression analysis showed that age, disease duration, medication mode, and the occurrence of diabetic peripheral neuropathy (DPN) were associated with the incidence of DR in diabetic patients, and that disease duration, the occurrence of DPN, and diabetic nephropathy were associated with the occurrence of VTDR. CONCLUSIONS: The prevalence of DR in the communities of Shenzhen is high. Age, disease duration, medications, and DPN are the major risk factors for the occurrence of DR.
BACKGROUND: To understand the prevalence of diabetic retinopathy (DR) in Shenzhen and to analyze the risk factors for the occurrence and development of DR. Based on the comprehensive information system for diabetes prevention and control in the communities of Shenzhen in 2019, six community health service centers in Shenzhen were used as research sites to carry out multicenter, cross-sectional screening studies. METHODS: Cluster random sampling was used to collect data from 904 patients with diabetes in Shenzhen. The occurrence of DR and vision-threatening diabetic retinopathy (VTDR) was analyzed, and multivariate logistic regression was performed to analyze the risk factors for DR and VTDR. EpiData version 3.1 (EpiData Association, Odense, Denmark) statistical software was used to build a database, and Statistical Package for the Social Sciences (SPSS) version 25.0 (IBM Corp., Armonk, N.Y., USA) was used to sort up and analyze the data. RESULTS: The prevalence of DR among diabeticpatients in Shenzhen was 18.58% [95% confidence interval (CI): 16.13-21.3%], and the prevalence of VTDR was 2.43% (95% CI: 1.57-1.2%). The prevalence of DR and VTDR was higher in males than in females. Logistic regression analysis showed that age, disease duration, medication mode, and the occurrence of diabetic peripheral neuropathy (DPN) were associated with the incidence of DR in diabeticpatients, and that disease duration, the occurrence of DPN, and diabetic nephropathy were associated with the occurrence of VTDR. CONCLUSIONS: The prevalence of DR in the communities of Shenzhen is high. Age, disease duration, medications, and DPN are the major risk factors for the occurrence of DR.