Literature DB >> 33545058

NLRP1: a jack of all trades, or a master of one?

Daniel A Bachovchin1.   

Abstract

Recent studies provide evidence that two chemically and mechanistically distinct signals activate the human NLRP1 inflammasome, challenging the concept that it-like other mammalian inflammasomes characterized thus far-evolved to detect and respond to a single danger-associated molecular pattern.
Copyright © 2021 Elsevier Inc. All rights reserved.

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Year:  2021        PMID: 33545058     DOI: 10.1016/j.molcel.2021.01.001

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  3 in total

Review 1.  Inflammasome activation: from molecular mechanisms to autoinflammation.

Authors:  Samuel Lara-Reyna; Emily A Caseley; Joanne Topping; François Rodrigues; Jorge Jimenez Macias; Sean E Lawler; Michael F McDermott
Journal:  Clin Transl Immunology       Date:  2022-07-07

2.  M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome.

Authors:  Sahana D Rao; Qifeng Chen; Qinghui Wang; Elizabeth L Orth-He; Michelle Saoi; Andrew R Griswold; Abir Bhattacharjee; Daniel P Ball; Hsin-Che Huang; Ashley J Chui; Dominic J Covelli; Shaochen You; Justin R Cross; Daniel A Bachovchin
Journal:  Nat Chem Biol       Date:  2022-02-14       Impact factor: 16.174

Review 3.  Nod-Like Receptors in Host Defence and Disease at the Epidermal Barrier.

Authors:  Judit Danis; Mark Mellett
Journal:  Int J Mol Sci       Date:  2021-04-28       Impact factor: 5.923

  3 in total

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