Literature DB >> 33541711

Transcriptome-Guided Design of Physiological Multilineage Liver Organoids.

Shijia Zhu1, Naoto Kubota1, Yujin Hoshida2.   

Abstract

Despite several technical challenges, human induced pluripotent stem cell (hiPSC)-derived organoids enable biologically and clinically relevant functional study of physiology and disease. In a recent Cell Systems article, Velazquez et al. report a novel strategy to identify regulators of multilineage organoid maturation by reverse-engineering from the global transcriptome of human tissues.
Copyright © 2021. Published by Elsevier Ltd.

Entities:  

Keywords:  gene regulatory network; human induced pluripotent stem cell; organogenesis

Mesh：

Year:  2021        PMID： 33541711      PMCID： PMC9037672          DOI： 10.1016/j.tig.2021.01.007

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.821


  9 in total

Review 1.  Microfluidic bioprinting for organ-on-a-chip models.

Authors:  Fang Yu; Deepak Choudhury
Journal:  Drug Discov Today       Date:  2019-03-30       Impact factor: 7.851

2.  Recapitulating macro-scale tissue self-organization through organoid bioprinting.

Authors:  Jonathan A Brassard; Mike Nikolaev; Tania Hübscher; Moritz Hofer; Matthias P Lutolf
Journal:  Nat Mater       Date:  2020-09-21       Impact factor: 43.841

3.  Uncovering Biological Factors That Regulate Hepatocellular Carcinoma Growth Using Patient-Derived Xenograft Assays.

Authors:  Min Zhu; Lin Li; Tianshi Lu; Hyesun Yoo; Ji Zhu; Purva Gopal; Sam C Wang; Matthew R Porembka; Nicole E Rich; Sofia Kagan; Mobolaji Odewole; Veronica Renteria; Akbar K Waljee; Tao Wang; Amit G Singal; Adam C Yopp; Hao Zhu
Journal:  Hepatology       Date:  2020-09-02       Impact factor: 17.425

Review 4.  Modeling Development and Disease with Organoids.

Authors:  Hans Clevers
Journal:  Cell       Date:  2016-06-16       Impact factor: 41.582

5.  Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids.

Authors:  Jeremy J Velazquez; Ryan LeGraw; Farzaneh Moghadam; Yuqi Tan; Jacquelyn Kilbourne; Joseph C Maggiore; Joshua Hislop; Silvia Liu; Davy Cats; Susana M Chuva de Sousa Lopes; Christopher Plaisier; Patrick Cahan; Samira Kiani; Mo R Ebrahimkhani
Journal:  Cell Syst       Date:  2020-12-07       Impact factor: 10.304

Review 6.  Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells.

Authors:  Beatrice Xuan Ho; Nicole Min Qian Pek; Boon-Seng Soh
Journal:  Int J Mol Sci       Date:  2018-03-21       Impact factor: 5.923

7.  Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform.

Authors:  Kevin Achberger; Christopher Probst; Jasmin Haderspeck; Sylvia Bolz; Julia Rogal; Johanna Chuchuy; Marina Nikolova; Virginia Cora; Lena Antkowiak; Wadood Haq; Nian Shen; Katja Schenke-Layland; Marius Ueffing; Stefan Liebau; Peter Loskill
Journal:  Elife       Date:  2019-08-27       Impact factor: 8.140

8.  Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6.

Authors:  Patrick Guye; Mohammad R Ebrahimkhani; Nathan Kipniss; Jeremy J Velazquez; Eldi Schoenfeld; Samira Kiani; Linda G Griffith; Ron Weiss
Journal:  Nat Commun       Date:  2016-01-06       Impact factor: 14.919

Review 9.  The Role of Sinusoidal Endothelial Cells in the Axis of Inflammation and Cancer Within the Liver.

Authors:  Alex L Wilkinson; Maria Qurashi; Shishir Shetty
Journal:  Front Physiol       Date:  2020-08-28       Impact factor: 4.566
  9 in total

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