Chitosan nanoparticles based on their derivatives as antioxidant and antibacterial additives for active bioplastic packaging.

Chitosan nanoparticles (CSNPs) based on their different derivatives were proposed as antioxidant and antimicrobial additives for active bioplastic packaging. Chitosan was modified with polyethylene glycol methyl ether methacrylate (PEGMA), stearyl methacrylate (SMA) and deoxycholic acid (DC) using radiation-induced graft polymerization and chemical conjugation. The modified CSNPs-g-pPEGMA, CSNPs-g-pSMA and CSNPs-DC self-assembled into nanoparticles with the size in the range of 25-60 nm. The CSNPs-DC derivative has superior antioxidant activity and the CSNPs-g-pSMA derivative exhibited outstanding antibacterial activity against growth of E.coli (95.33 %). All modified CSNPs showed their capacities to inhibit S.aureus bacterial growth (>98 %). PLA packaging films containing CSNPs-g-pSMA inhibited the growth of natural microorganism on bread slices. Different chemical functions of the CSNPs derivatives provided different gas permeability and mechanical properties of the PLA films. The CSNPs derivatives would be promising antioxidant and antimicrobial additives for bioplastics to be further used as bio-based active food packaging.