Sebastiano Rapisarda1, Maida Bada2, Andrea Polara2, Felice Crocetto3, Massimiliano Creta4, Francesco Chiancone5, Massimo Occhipinti1, Rossella Bertoloni2, Armando Marciano1, Luca Aresu1, Arjan Nazaraj1, Sara Grosso1, Gaetano Grosso1. 1. Department of Urology, Hospital Pederzoli, Peschiera del Garda, Verona (VR), Italy. 2. Department of Urology, Hospital S.Bassiano, Bassano del Grappa, VI, Italy. 3. Department of Neurosciences, Reproductive and Odontostomatological Sciences, Urology and Andrology Unit, University of Naples Federico II, Via Pansini No. 5, 80131, Naples, Italy. felice.crocetto@gmail.com. 4. Department of Neurosciences, Reproductive and Odontostomatological Sciences, Urology and Andrology Unit, University of Naples Federico II, Via Pansini No. 5, 80131, Naples, Italy. 5. Department of Urology, AORN A. Cardarelli, Naples, Italy.
Abstract
BACKGROUND: Primary malignant melanoma (PMM) of the bladder represents a very rare clinic-pathologic entity. Given the rarity of the disease, the best treatment option is not well recognized. CASE PRESENTATION: We describe a case of neoplasm of the bladder in a 74 years-old Caucasian man presenting with massive hematuria. Based on clinical, instrumental and histological findings a diagnosis of PMM was made. The patient underwent trans urethral resection of bladder tumor plus intravesical Bacillus Calmette-Guérin. CONCLUSIONS: To make a correct diagnosis, clinical history, endoscopic evaluation, histopathological examination and immunohistochemistry, are necessary. Multidisciplinary evaluation is required to discriminate primary from metastatic malignant melanoma.
BACKGROUND:Primary malignant melanoma (PMM) of the bladder represents a very rare clinic-pathologic entity. Given the rarity of the disease, the best treatment option is not well recognized. CASE PRESENTATION: We describe a case of neoplasm of the bladder in a 74 years-old Caucasian man presenting with massive hematuria. Based on clinical, instrumental and histological findings a diagnosis of PMM was made. The patient underwent trans urethral resection of bladder tumor plus intravesical Bacillus Calmette-Guérin. CONCLUSIONS: To make a correct diagnosis, clinical history, endoscopic evaluation, histopathological examination and immunohistochemistry, are necessary. Multidisciplinary evaluation is required to discriminate primary from metastatic malignant melanoma.