Literature DB >> 33539214

Rationale for the Role of Heparin and Related GAG Antithrombotics in COVID-19 Infection.

Harry N Magnani1.   

Abstract

The SARS-CoV-2 pandemic has focused attention on prevention, restriction and treatment methods that are acceptable worldwide. This means that they should be simple and inexpensive. This review examines the possible role of glycosaminoglycan (GAG) antithrombotics in the treatment of COVID-19. The pathophysiology of this disease reveals a complex interplay between the hemostatic and immune systems that can be readily disrupted by SARS-CoV-2. Some of the GAG antithrombotics also possess immune-modulatory actions and since they are relatively inexpensive they could play an important role in the management of COVID-19 and its complications.

Entities:  

Keywords:  COVID-19; GAG-antithrombotics; danaparoid sodium; pathophysiology; sulodexide

Mesh：

Substances：

Year:  2021        PMID： 33539214     DOI： 10.1177/1076029620977702

Source DB:  PubMed          Journal:  Clin Appl Thromb Hemost        ISSN： 1076-0296            Impact factor:   2.389


  6 in total

1.  Sulodexide Significantly Improves Endothelial Dysfunction and Alleviates Chest Pain and Palpitations in Patients With Long-COVID-19: Insights From TUN-EndCOV Study.

Authors:  Salma Charfeddine; Hassen Ibnhadjamor; Jihen Jdidi; Slim Torjmen; Salma Kraiem; Amine Bahloul; Ahmed Makni; Nesrine Kallel; Nedia Moussa; Mariem Boudaya; Imen Touil; Aiman Ghrab; Jamel Elghoul; Zeineb Meddeb; Yamina Thabet; Kais Ben Salem; Faouzi Addad; Kamel Bouslama; Sami Milouchi; Rania Hammami; Salem Abdessalem; Leila Abid
Journal:  Front Cardiovasc Med       Date:  2022-05-12

Review 2.  Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease.

Authors:  Robin Caird; Michael Williamson; Azeez Yusuf; Debananda Gogoi; Michelle Casey; Noel G McElvaney; Emer P Reeves
Journal:  Int J Mol Sci       Date:  2022-06-08       Impact factor: 6.208

3.  COVID-19-related dynamic coagulation disturbances and anticoagulation strategies using conventional D-dimer and point-of-care Sonoclot tests: a prospective cohort study.

Authors:  Madhumita Premkumar; Sekar Loganathan; Kamal Kajal; Amarjyoti Hazarika; Shiv Soni; Goverdhan Dutt Puri; Inderpaul Singh Sehgal; Vikas Suri; Pankaj Malhotra; Virendra Singh; Ajay Duseja; Ashish Bhalla; Jasmina Ahluwalia; Narender Kumar; Kushal Kekan; Sant Ram; Karan Singla; Varun Mahajan; Narayana Yaddanapudi
Journal:  BMJ Open       Date:  2022-05-02       Impact factor: 3.006

4.  Experience of danaparoid to treat vaccine-induced immune thrombocytopenia and thrombosis, VITT.

Authors:  Lasse Myllylahti; Hanna Pitkänen; Harry Magnani; Riitta Lassila
Journal:  Thromb J       Date:  2022-02-04

5.  Do Circulating Histones Represent the Missing Link among COVID-19 Infection and Multiorgan Injuries, Microvascular Coagulopathy and Systemic Hyperinflammation?

Authors:  Daniela Ligi; Rosanna Maniscalco; Mario Plebani; Giuseppe Lippi; Ferdinando Mannello
Journal:  J Clin Med       Date:  2022-03-24       Impact factor: 4.241

6.  Sulodexide: A Benefit for Cardiovascular Sequelae of Long COVID Patients?

Authors:  Győző Szolnoky; Alejandro José González-Ochoa
Journal:  Clin Appl Thromb Hemost       Date:  2022 Jan-Dec       Impact factor: 2.389
  6 in total

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