Literature DB >> 33539127

An examination of genetic and environmental factors related to negative personality traits, educational attainment, and economic success.

Michael C Stallings1, Tricia Neppl2.   

Abstract

Personality variables are associated with educational attainment and socioeconomic outcomes. In this study we incorporated a polygenic score derived from the largest genome-wide association study (GWAS) of educational attainment to date (Lee et al., 2018) into the Interactionist Model of R. D. Conger, Martin, and Masarik (2021) that describes the influence of socioeconomic factors on individual development. The inclusion of a polygenic score predictive of educational attainment (PS-Edu) into this model, and the use of the multigeneration, longitudinal Family Transitions Project (FTP) provide a unique opportunity to investigate genetic and environmental influences on the development of negative personality traits and educational and economic outcomes. The FTP is a three-generation sample. This study utilized data from the first generation (G1; mean age 40 at initiation of the FTP) and second generation (G2; assessed at mean ages 18 and 30). Participants are approximately 50% female, 99% of European ancestry, primarily from lower to middle class SES. PS-Edu was significantly correlated with educational attainment in both generations of the FTP, accounting for 4.1 to 6.7% of the variance. Findings confirm that PS-Edu is a complex genetic index that is correlated with all of the socioeconomic constructs in the model. Results suggest potential gene-environment correlation or common genetic influences underlie associations among parenting investments, negative personality traits, and educational attainment. Genetic variance captured by PS-Edu was mediated substantially through G1 parental investments. Although study limitations warrant cautious interpretation, we demonstrate the promise of including polygenic scores in developmental models to better understand genetic and environmental influences on human development. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Entities:  

Mesh:

Year:  2021        PMID: 33539127      PMCID: PMC8269749          DOI: 10.1037/dev0001131

Source DB:  PubMed          Journal:  Dev Psychol        ISSN: 0012-1649


  37 in total

1.  minimac2: faster genotype imputation.

Authors:  Christian Fuchsberger; Gonçalo R Abecasis; David A Hinds
Journal:  Bioinformatics       Date:  2014-10-22       Impact factor: 6.937

2.  Special section on personality development: Testing environmental and genetic associations across generations.

Authors:  Katherine Jewsbury Conger; Tricia K Neppl; Laura Scaramella
Journal:  Dev Psychol       Date:  2021-02

3.  Polygenic score for educational attainment captures DNA variants shared between personality traits and educational achievement.

Authors:  Emily Smith-Woolley; Saskia Selzam; Robert Plomin
Journal:  J Pers Soc Psychol       Date:  2019-03-28

4.  Educational Attainment and Personality Are Genetically Intertwined.

Authors:  René Mõttus; Anu Realo; Uku Vainik; Jüri Allik; Tõnu Esko
Journal:  Psychol Sci       Date:  2017-09-14

5.  Childhood personality as a harbinger of competence and resilience in adulthood.

Authors:  Rebecca L Shiner; Ann S Masten
Journal:  Dev Psychopathol       Date:  2012-05

6.  Meta-analysis of genome-wide association studies for personality.

Authors:  M H M de Moor; P T Costa; A Terracciano; R F Krueger; E J C de Geus; T Toshiko; B W J H Penninx; T Esko; P A F Madden; J Derringer; N Amin; G Willemsen; J-J Hottenga; M A Distel; M Uda; S Sanna; P Spinhoven; C A Hartman; P Sullivan; A Realo; J Allik; A C Heath; M L Pergadia; A Agrawal; P Lin; R Grucza; T Nutile; M Ciullo; D Rujescu; I Giegling; B Konte; E Widen; D L Cousminer; J G Eriksson; A Palotie; L Peltonen; M Luciano; A Tenesa; G Davies; L M Lopez; N K Hansell; S E Medland; L Ferrucci; D Schlessinger; G W Montgomery; M J Wright; Y S Aulchenko; A C J W Janssens; B A Oostra; A Metspalu; G R Abecasis; I J Deary; K Räikkönen; L J Bierut; N G Martin; C M van Duijn; D I Boomsma
Journal:  Mol Psychiatry       Date:  2010-12-21       Impact factor: 15.992

7.  Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:  Aysu Okbay; Bart M L Baselmans; Jan-Emmanuel De Neve; Patrick Turley; Michel G Nivard; Mark Alan Fontana; S Fleur W Meddens; Richard Karlsson Linnér; Cornelius A Rietveld; Jaime Derringer; Jacob Gratten; James J Lee; Jimmy Z Liu; Ronald de Vlaming; Tarunveer S Ahluwalia; Jadwiga Buchwald; Alana Cavadino; Alexis C Frazier-Wood; Nicholas A Furlotte; Victoria Garfield; Marie Henrike Geisel; Juan R Gonzalez; Saskia Haitjema; Robert Karlsson; Sander W van der Laan; Karl-Heinz Ladwig; Jari Lahti; Sven J van der Lee; Penelope A Lind; Tian Liu; Lindsay Matteson; Evelin Mihailov; Michael B Miller; Camelia C Minica; Ilja M Nolte; Dennis Mook-Kanamori; Peter J van der Most; Christopher Oldmeadow; Yong Qian; Olli Raitakari; Rajesh Rawal; Anu Realo; Rico Rueedi; Börge Schmidt; Albert V Smith; Evie Stergiakouli; Toshiko Tanaka; Kent Taylor; Gudmar Thorleifsson; Juho Wedenoja; Juergen Wellmann; Harm-Jan Westra; Sara M Willems; Wei Zhao; Najaf Amin; Andrew Bakshi; Sven Bergmann; Gyda Bjornsdottir; Patricia A Boyle; Samantha Cherney; Simon R Cox; Gail Davies; Oliver S P Davis; Jun Ding; Nese Direk; Peter Eibich; Rebecca T Emeny; Ghazaleh Fatemifar; Jessica D Faul; Luigi Ferrucci; Andreas J Forstner; Christian Gieger; Richa Gupta; Tamara B Harris; Juliette M Harris; Elizabeth G Holliday; Jouke-Jan Hottenga; Philip L De Jager; Marika A Kaakinen; Eero Kajantie; Ville Karhunen; Ivana Kolcic; Meena Kumari; Lenore J Launer; Lude Franke; Ruifang Li-Gao; David C Liewald; Marisa Koini; Anu Loukola; Pedro Marques-Vidal; Grant W Montgomery; Miriam A Mosing; Lavinia Paternoster; Alison Pattie; Katja E Petrovic; Laura Pulkki-Råback; Lydia Quaye; Katri Räikkönen; Igor Rudan; Rodney J Scott; Jennifer A Smith; Angelina R Sutin; Maciej Trzaskowski; Anna E Vinkhuyzen; Lei Yu; Delilah Zabaneh; John R Attia; David A Bennett; Klaus Berger; Lars Bertram; Dorret I Boomsma; Harold Snieder; Shun-Chiao Chang; Francesco Cucca; Ian J Deary; Cornelia M van Duijn; Johan G Eriksson; Ute Bültmann; Eco J C de Geus; Patrick J F Groenen; Vilmundur Gudnason; Torben Hansen; Catharine A Hartman; Claire M A Haworth; Caroline Hayward; Andrew C Heath; David A Hinds; Elina Hyppönen; William G Iacono; Marjo-Riitta Järvelin; Karl-Heinz Jöckel; Jaakko Kaprio; Sharon L R Kardia; Liisa Keltikangas-Järvinen; Peter Kraft; Laura D Kubzansky; Terho Lehtimäki; Patrik K E Magnusson; Nicholas G Martin; Matt McGue; Andres Metspalu; Melinda Mills; Renée de Mutsert; Albertine J Oldehinkel; Gerard Pasterkamp; Nancy L Pedersen; Robert Plomin; Ozren Polasek; Christine Power; Stephen S Rich; Frits R Rosendaal; Hester M den Ruijter; David Schlessinger; Helena Schmidt; Rauli Svento; Reinhold Schmidt; Behrooz Z Alizadeh; Thorkild I A Sørensen; Tim D Spector; John M Starr; Kari Stefansson; Andrew Steptoe; Antonio Terracciano; Unnur Thorsteinsdottir; A Roy Thurik; Nicholas J Timpson; Henning Tiemeier; André G Uitterlinden; Peter Vollenweider; Gert G Wagner; David R Weir; Jian Yang; Dalton C Conley; George Davey Smith; Albert Hofman; Magnus Johannesson; David I Laibson; Sarah E Medland; Michelle N Meyer; Joseph K Pickrell; Tõnu Esko; Robert F Krueger; Jonathan P Beauchamp; Philipp D Koellinger; Daniel J Benjamin; Meike Bartels; David Cesarini
Journal:  Nat Genet       Date:  2016-04-18       Impact factor: 38.330

8.  Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank.

Authors:  W David Hill; Saskia P Hagenaars; Riccardo E Marioni; Sarah E Harris; David C M Liewald; Gail Davies; Aysu Okbay; Andrew M McIntosh; Catharine R Gale; Ian J Deary
Journal:  Curr Biol       Date:  2016-11-03       Impact factor: 10.834

9.  The genetic and environmental origins of learning abilities and disabilities in the early school years.

Authors:  Yulia Kovas; Claire M A Haworth; Philip S Dale; Robert Plomin
Journal:  Monogr Soc Res Child Dev       Date:  2007

10.  Power and predictive accuracy of polygenic risk scores.

Authors:  Frank Dudbridge
Journal:  PLoS Genet       Date:  2013-03-21       Impact factor: 5.917

View more
  1 in total

1.  Socioeconomic origin, future expectations, and educational achievement: A longitudinal three-generation study of the persistence of family advantage.

Authors:  Kaspar Burger; Jeylan T Mortimer
Journal:  Dev Psychol       Date:  2021-09
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.