Literature DB >> 33537957

Patients' perception on the quality of care for multiple endocrine neoplasia disorders in Europe: an online survey from a patient support group.

Karl Philipp Drewitz1,2,3, Jo Grey4,5,6, Petra Brügmann4,7,6, Josef Pichl4,7, Martina Sammarco4,8, Monique Aarts4,9, Dirk van Genechten4,10, Maria-Luisa Brandi4,11,12, Ludwig Schaaf4,13.   

Abstract

PURPOSE: European Patient Advocacy Groups (ePAGs) within the Endo-ERN identified a lack of knowledge about quality of care (QoC) of patients with multiple endocrine neoplasia (MEN). The aim of this study was to identify inequalities in care and to encourage improvements.
METHODS: The European MEN Alliance (EMENA) developed and conducted a survey, using the European Commissions' EUSurvey platform. Patient groups and healthcare professionals (HCPs) distributed the survey.
RESULTS: A total of 288 participants completed the survey (MEN1 n = 203, MEN2 n = 67, MEN3 n = 18) from 18 European countries. The majority of respondents were recruited via patient groups (58%), aged between 41 and 60 years (53%) and were female (67%). All participants reported having been diagnosed on average 5.58 years (95%-CI: 4.45-6.60) after first symptoms occurred. This timeframe was lower in the group with MEN2 (2.97 years, 95%-CI: 1.37-4.57). Most of the participants (67%) received their diagnosis by a positive gene test after presenting with one or more MEN-related tumours. Overall QoC was rated as either "good" (43%) or "excellent" (36%).
CONCLUSION: The results of this unique Europe-wide, patient-driven survey on QoC of patients with MEN show that ratings for overall QoC were lower than ratings for different aspects of care. This may be because of the complex nature of care for genetic syndromes. Furthermore, patients who connect with patient groups may be deemed "expert patients" whose answers are not representative of the overall MEN patient community. We hope that Endo-ERN can support further education and training for HCPs based on these results.

Entities:  

Keywords:  Endocrine tumours; Multiple endocrine neoplasia; Patient report; Quality of care; Rare diseases

Mesh:

Year:  2021        PMID: 33537957     DOI: 10.1007/s12020-021-02637-w

Source DB:  PubMed          Journal:  Endocrine        ISSN: 1355-008X            Impact factor:   3.633


  22 in total

Review 1.  Multiple endocrine neoplasia--syndromes of the twentieth century.

Authors:  R V Thakker
Journal:  J Clin Endocrinol Metab       Date:  1998-08       Impact factor: 5.958

2.  Positional cloning of the gene for multiple endocrine neoplasia-type 1.

Authors:  S C Chandrasekharappa; S C Guru; P Manickam; S E Olufemi; F S Collins; M R Emmert-Buck; L V Debelenko; Z Zhuang; I A Lubensky; L A Liotta; J S Crabtree; Y Wang; B A Roe; J Weisemann; M S Boguski; S K Agarwal; M B Kester; Y S Kim; C Heppner; Q Dong; A M Spiegel; A L Burns; S J Marx
Journal:  Science       Date:  1997-04-18       Impact factor: 47.728

Review 3.  Genetic basis of endocrine disease: multiple endocrine neoplasia type 2.

Authors:  L M Mulligan; B A Ponder
Journal:  J Clin Endocrinol Metab       Date:  1995-07       Impact factor: 5.958

Review 4.  Multiple Endocrine Neoplasia: A Genetically Diverse Group of Familial Tumor Syndromes.

Authors:  M Cristina Pacheco
Journal:  J Pediatr Genet       Date:  2016-03-09

Review 5.  Multiple endocrine neoplasia: an update.

Authors:  Jane E McDonnell; Matti L Gild; Roderick J Clifton-Bligh; Bruce G Robinson
Journal:  Intern Med J       Date:  2019-08       Impact factor: 2.048

6.  MEN1 redefined, a clinical comparison of mutation-positive and mutation-negative patients.

Authors:  Joanne M de Laat; Rob B van der Luijt; Carolina R C Pieterman; Maria P Oostveen; Ad R Hermus; Olaf M Dekkers; Wouter W de Herder; Anouk N van der Horst-Schrivers; Madeleine L Drent; Peter H Bisschop; Bas Havekes; Menno R Vriens; Gerlof D Valk
Journal:  BMC Med       Date:  2016-11-15       Impact factor: 8.775

Review 7.  Multiple endocrine neoplasia type 2: an overview.

Authors:  Jessica Moline; Charis Eng
Journal:  Genet Med       Date:  2011-09       Impact factor: 8.822

Review 8.  Multiple endocrine neoplasia (MEN) syndromes.

Authors:  Gerard V Walls
Journal:  Semin Pediatr Surg       Date:  2014-03-15       Impact factor: 2.754

Review 9.  Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4).

Authors:  Rajesh V Thakker
Journal:  Mol Cell Endocrinol       Date:  2013-08-08       Impact factor: 4.102

Review 10.  Multiple Endocrine Neoplasia Syndromes from Genetic and Epigenetic Perspectives.

Authors:  Fatemeh Khatami; Seyed Mohammad Tavangar
Journal:  Biomark Insights       Date:  2018-07-02
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.