Literature DB >> 33537407

Pediatric Toxidrome Simulation Curriculum: Lidocaine-Induced Methemoglobinemia.

Chelsea Del Rosso1, Anita Thomas2, Nicole Hardy3, Scott Connelly4, Ulysses Davila5, Jean Pearce6, Suzan Mazor7, Rebekah Burns8.   

Abstract

Introduction: Lidocaine is a common local anesthetic used during minor procedures performed on pediatric patients. A rare but toxic and life-threatening side effect of lidocaine is methemoglobinemia. It should be considered in children who are hypoxic after exposure to an oxidizing agent.
Methods: We developed this simulation case for pediatric emergency medicine (PEM) fellows, but it can be adapted for interprofessional simulation. The case involved a 1-month-old male with hypoxia and resulting central cyanosis after exposure to lidocaine. The team performed an initial evaluation and intervention, collected a history, and developed a differential diagnosis for hypoxia and central cyanosis in an infant. Methemoglobinemia was confirmed by CO-oximetry. Preparatory materials, a debriefing guide, and scenario evaluation forms assisted with facilitation.
Results: Fifty-six participants (including 18 PEM fellows) completed this simulation across four institutions. Participants rated the scenario on a 5-point Likert scale (1 = strongly disagree, 5 = strongly agree), finding it to be relevant to their work (median = 5) and realistic (median = 5). After participation in the simulation, learners felt confident in their ability to recognize methemoglobinemia (median = 4) and implement a plan to stabilize an infant with hypoxia (median = 4). Discussion: This simulation represents a resource for learners in the pediatric emergency department. It teaches the recognition and management of an infant with lidocaine toxicity and resultant methemoglobinemia. It uses experiential learning to teach and reinforce a systematic approach to the evaluation and management of a critically ill infant with acquired methemoglobinemia.
© 2021 Rosso et al.

Entities:  

Keywords:  Emergency Medicine; Methemoglobinemia; Pediatric Emergency Medicine; Simulation; Simulation Curriculum; Toxicological Phenomena; Toxicology

Mesh:

Substances:

Year:  2021        PMID: 33537407      PMCID: PMC7842087          DOI: 10.15766/mep_2374-8265.11089

Source DB:  PubMed          Journal:  MedEdPORTAL        ISSN: 2374-8265


  8 in total

1.  The oxyhaemoglobin dissociation curve in critical illness.

Authors:  T J Morgan
Journal:  Crit Care Resusc       Date:  1999-03       Impact factor: 2.159

Review 2.  Focus on diagnosis: co-oximetry.

Authors:  Elizabeth Mack
Journal:  Pediatr Rev       Date:  2007-02

Review 3.  Methemoglobinemia: a review and recommendations for management.

Authors:  Jessica A Cortazzo; Adam D Lichtman
Journal:  J Cardiothorac Vasc Anesth       Date:  2013-08-13       Impact factor: 2.628

Review 4.  Methemoglobinemia: pathogenesis, diagnosis, and management.

Authors:  Anna Skold; Dominique L Cosco; Robin Klein
Journal:  South Med J       Date:  2011-11       Impact factor: 0.954

5.  Congenital methemoglobinemia: a rare cause of cyanosis in the newborn--a case report.

Authors:  Shonola S Da-Silva; Imran S Sajan; Joseph P Underwood
Journal:  Pediatrics       Date:  2003-08       Impact factor: 7.124

6.  Studies of the efficacy and potential hazards of methylene blue therapy in aniline-induced methaemoglobinaemia.

Authors:  J W Harvey; A S Keitt
Journal:  Br J Haematol       Date:  1983-05       Impact factor: 6.998

7.  Pediatric Emergency Medicine Simulation Curriculum: Marijuana Ingestion.

Authors:  Carson Burns; Rebekah Burns; Elizabeth Sanseau; Suzan Mazor; Jennifer Reid; Kimberly Stone; Anita Thomas
Journal:  MedEdPORTAL       Date:  2018-12-07

8.  Pediatric Toxidrome Simulation Curriculum: Bupropion Overdose.

Authors:  Emily Hartford; Anita Thomas; Ashley Keilman; Neil Uspal; Kimberly Stone; Jennifer Reid; Rebekah Burns
Journal:  MedEdPORTAL       Date:  2019-10-25
  8 in total

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