Literature DB >> 33536597

Mutation alters chromatin changes during injury response to drive cancer.

Dane Vassiliadis, Mark A Dawson.   

Abstract

Entities:  

Keywords:  Cancer; Epigenetics; Medical research

Mesh：

Substances：

Year:  2021        PMID： 33536597     DOI： 10.1038/d41586-021-00211-y

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   69.504


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  8 in total

1.  Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.

Authors:  Pawel K Mazur; Alexander Herner; Stephano S Mello; Matthias Wirth; Simone Hausmann; Francisco J Sánchez-Rivera; Shane M Lofgren; Timo Kuschma; Stephan A Hahn; Deepak Vangala; Marija Trajkovic-Arsic; Aayush Gupta; Irina Heid; Peter B Noël; Rickmer Braren; Mert Erkan; Jörg Kleeff; Bence Sipos; Leanne C Sayles; Mathias Heikenwalder; Elisabeth Heßmann; Volker Ellenrieder; Irene Esposito; Tyler Jacks; James E Bradner; Purvesh Khatri; E Alejandro Sweet-Cordero; Laura D Attardi; Roland M Schmid; Guenter Schneider; Julien Sage; Jens T Siveke
Journal:  Nat Med       Date:  2015-09-21       Impact factor: 53.440

2.  Mutant Kras co-opts a proto-oncogenic enhancer network in inflammation-induced metaplastic progenitor cells to initiate pancreatic cancer.

Authors:  Yong Li; Yi He; Junya Peng; Zhendong Su; Zeyao Li; Bingjie Zhang; Jing Ma; Meilian Zhuo; Di Zou; Xinde Liu; Xinhong Liu; Wenze Wang; Dan Huang; Mengyue Xu; Jianbin Wang; Haiteng Deng; Jing Xue; Wei Xie; Xun Lan; Mo Chen; Yupei Zhao; Wenming Wu; Charles J David
Journal:  Nat Cancer       Date:  2020-11-02

3.  Master transcription factors and mediator establish super-enhancers at key cell identity genes.

Authors:  Warren A Whyte; David A Orlando; Denes Hnisz; Brian J Abraham; Charles Y Lin; Michael H Kagey; Peter B Rahl; Tong Ihn Lee; Richard A Young
Journal:  Cell       Date:  2013-04-11       Impact factor: 41.582

4.  Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.

Authors:  Omer Gilan; Inmaculada Rioja; Rab K Prinjha; Mark A Dawson; Kathy Knezevic; Matthew J Bell; Miriam M Yeung; Nicola R Harker; Enid Y N Lam; Chun-Wa Chung; Paul Bamborough; Massimo Petretich; Marjeta Urh; Stephen J Atkinson; Anna K Bassil; Emma J Roberts; Dane Vassiliadis; Marian L Burr; Alex G S Preston; Christopher Wellaway; Thilo Werner; James R Gray; Anne-Marie Michon; Thomas Gobbetti; Vinod Kumar; Peter E Soden; Andrea Haynes; Johanna Vappiani; David F Tough; Simon Taylor; Sarah-Jane Dawson; Marcus Bantscheff; Matthew Lindon; Gerard Drewes; Emmanuel H Demont; Danette L Daniels; Paola Grandi
Journal:  Science       Date:  2020-03-19       Impact factor: 47.728

Review 5.  Chronic pancreatitis.

Authors:  Georg Beyer; Aida Habtezion; Jens Werner; Markus M Lerch; Julia Mayerle
Journal:  Lancet       Date:  2020-08-15       Impact factor: 79.321

6.  Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice.

Authors:  Nils Habbe; Guanglu Shi; Robert A Meguid; Volker Fendrich; Farzad Esni; Huiping Chen; Georg Feldmann; Doris A Stoffers; Stephen F Konieczny; Steven D Leach; Anirban Maitra
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-21       Impact factor: 11.205

7.  Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice.

Authors:  Carmen Guerra; Alberto J Schuhmacher; Marta Cañamero; Paul J Grippo; Lena Verdaguer; Lucía Pérez-Gallego; Pierre Dubus; Eric P Sandgren; Mariano Barbacid
Journal:  Cancer Cell       Date:  2007-03       Impact factor: 31.743

8.  A gene-environment-induced epigenetic program initiates tumorigenesis.

Authors:  Direna Alonso-Curbelo; Yu-Jui Ho; Cassandra Burdziak; Jesper L V Maag; John P Morris; Rohit Chandwani; Hsuan-An Chen; Kaloyan M Tsanov; Francisco M Barriga; Wei Luan; Nilgun Tasdemir; Geulah Livshits; Elham Azizi; Jaeyoung Chun; John E Wilkinson; Linas Mazutis; Steven D Leach; Richard Koche; Dana Pe'er; Scott W Lowe
Journal:  Nature       Date:  2021-02-03       Impact factor: 49.962
  8 in total
  1 in total

1.  Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma.

Authors:  Xiang Wang; Chunliang Liu; Jianan Chen; Lei Chen; Xianwen Ren; Minghui Hou; Xiuliang Cui; Youhai Jiang; Erdong Liu; Yali Zong; Anqi Duan; Xiaohui Fu; Wenlong Yu; Xiaofang Zhao; Zhao Yang; Yongjie Zhang; Jing Fu; Hongyang Wang
Journal:  Cell Discov       Date:  2022-10-05       Impact factor: 38.079
  1 in total

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