Literature DB >> 33535788

New Insight Into Metformin-Induced Cholesterol-Lowering Effect Crosstalk Between Glucose and Cholesterol Homeostasis via ChREBP (Carbohydrate-Responsive Element-Binding Protein)-Mediated PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Regulation.

Die Hu1,2, Yanhong Guo2, Renrong Wu3, Tiannan Shao3, Junke Long1, Bilian Yu1, Huilun Wang1,2, Yonghong Luo1,2, Haocheng Lu1,2, Jifeng Zhang1,2, Y Eugene Chen1,2, Daoquan Peng1.   

Abstract

[Figure: see text].

Entities:  

Keywords:  cholesterol; diabetes; glucose; hepatocyte; liver; metformin

Year:  2021        PMID： 33535788     DOI： 10.1161/ATVBAHA.120.315708

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


  8 in total

1.  Metformin enhances LDL-cholesterol uptake by suppressing the expression of the pro-protein convertase subtilisin/kexin type 9 (PCSK9) in liver cells.

Authors:  Amjad Ali; Hema Unnikannan; Jasmin Shafarin; Khuloud Bajbouj; Jalal Taneera; Jibran Sualeh Muhammad; Haydar Hasan; Albert Salehi; Samir Awadallah; Mawieh Hamad
Journal:  Endocrine       Date:  2022-03-02       Impact factor: 3.925

2.  Metformin Ameliorates Hepatic Steatosis induced by olanzapine through inhibiting LXRα/PCSK9 pathway.

Authors:  Wenqiang Zhu; Chen Ding; Piaopiao Huang; Juanli Ran; Pingan Lian; Yaxin Tang; Wen Dai; Xiansheng Huang
Journal:  Sci Rep       Date:  2022-04-04       Impact factor: 4.996

Review 3.  Updated Understanding of the Crosstalk Between Glucose/Insulin and Cholesterol Metabolism.

Authors:  Xuan Xiao; Yonghong Luo; Daoquan Peng
Journal:  Front Cardiovasc Med       Date:  2022-04-29

4.  A comparative evaluation of cardiac and neurological safety status of two commonly used oral hypoglycaemic agents in T2-DM Swiss albino mice model.

Authors:  Md Ohidur Rahman; Shaheen Ahmed; Tanoy Mazumder; Md Abdus Salam; Prodip Kumar Baral; Md Faruk Rana; Shuvo Mitra; Sayem Hossain; Rubiya Rahman; Md Saddam Hussain
Journal:  Metabol Open       Date:  2022-05-23

5.  Endogenous PCSK9 may influence circulating CD45neg/CD34bright and CD45neg/CD34bright/CD146neg cells in patients with type 2 diabetes mellitus.

Authors:  Romina Tripaldi; Paola Lanuti; Paola Giustina Simeone; Rossella Liani; Giuseppina Bologna; Sonia Ciotti; Pasquale Simeone; Augusto Di Castelnuovo; Marco Marchisio; Francesco Cipollone; Francesca Santilli
Journal:  Sci Rep       Date:  2021-05-06       Impact factor: 4.379

6.  Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice.

Authors:  Jean Baptiste Nyandwi; Young Shin Ko; Hana Jin; Seung Pil Yun; Sang Won Park; Hye Jung Kim
Journal:  Biomolecules       Date:  2021-10-06

Review 7.  Old and Novel Therapeutic Approaches in the Management of Hyperglycemia, an Important Risk Factor for Atherosclerosis.

Authors:  Milijana Janjusevic; Alessandra Lucia Fluca; Giulia Gagno; Alessandro Pierri; Laura Padoan; Annamaria Sorrentino; Antonio Paolo Beltrami; Gianfranco Sinagra; Aneta Aleksova
Journal:  Int J Mol Sci       Date:  2022-02-20       Impact factor: 5.923

8.  Ellagic Acid Effect on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Authors:  Gladys Maribel Hidalgo-Lozada; Angélica Villarruel-López; Esperanza Martínez-Abundis; Olga Vázquez-Paulino; Manuel González-Ortiz; Karina Griselda Pérez-Rubio
Journal:  J Clin Med       Date:  2022-09-28       Impact factor: 4.964
  8 in total

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