Literature DB >> 33535485

Benzodiazepines: Their Use either as Essential Medicines or as Toxics Substances.

Edilma Sanabria1, Ronald Edgardo Cuenca1, Miguel Ángel Esteso2,3, Mauricio Maldonado4.   

Abstract

This review highlights the nature, characteristics, properties, pharmacological differences between different types of benzodiazepines, the mechanism of action in the central nervous system, and the degradation of benzodiazepines. In the end, the efforts to reduce the benzodiazepines' adverse effects are shown and a reflection is made on the responsible uses of these medications.

Entities:  

Keywords:  benzodiazepines; medical uses; toxicology

Year:  2021        PMID： 33535485      PMCID： PMC7912725          DOI： 10.3390/toxics9020025

Source DB:  PubMed          Journal:  Toxics        ISSN： 2305-6304


  63 in total

1.  The effects of bromazepam over the central and frontal areas during a motor task: an EEG study.

Authors:  Suzete Fortunato; Guaraci Ken Tanaka; Fernanda Araújo; Juliana Bittencourt; Danielle Aprigio; Mariana Gongora; Silmar Teixeira; Fernando Augusto Monteiro Saboia Pompeu; Mauricio Cagy; Luis F Basile; Pedro Ribeiro; Bruna Velasques
Journal:  Arq Neuropsiquiatr       Date:  2015-04-01       Impact factor: 1.420

2.  Resurgence of catatonia following tapering or stoppage of lorazepam - A case series and implications.

Authors:  Syed Farooq Ali; Guru S Gowda; T S Jaisoorya; Suresh Bada Math
Journal:  Asian J Psychiatr       Date:  2017-04-04

3.  Potential impurities of anxiolytic drug, clobazam: Identification, synthesis and characterization using HPLC, LC-ESI/MSn and NMR.

Authors:  Neeraj Kumar; Subba Rao Devineni; Shailendra Kumar Dubey; Pramod Kumar
Journal:  J Pharm Biomed Anal       Date:  2017-01-29       Impact factor: 3.935

4.  A Stereoselective Route to Tetrahydrobenzoxazepines and Tetrahydrobenzodiazepines via Ring-Opening and Aza-Michael Addition of Activated Aziridines with 2-Hydroxyphenyl and 2-Aminophenyl Acrylates.

Authors:  Chandan Kumar Shahi; Aditya Bhattacharyya; Yerramsetti Nanaji; Manas K Ghorai
Journal:  J Org Chem       Date:  2016-10-17       Impact factor: 4.354

Review 5.  [A pharmacological profile of clobazam (Mystan), a new antiepileptic drug].

Authors:  H Nakajima
Journal:  Nihon Yakurigaku Zasshi       Date:  2001-08

6.  [Suitability of the use of benzodiazepines prescribed by the pharmacist in the elderly. A doctor-pharmacist collaboration study].

Authors:  Josefina Velert Vila; M del Mar Velert Vila; Luis Salar Ibáñez; Juan Antonio Avellana Zaragoza; Lucrecia Moreno Royo
Journal:  Aten Primaria       Date:  2011-10-24       Impact factor: 1.137

Review 7.  Classics in chemical neuroscience: diazepam (valium).

Authors:  Nicholas E Calcaterra; James C Barrow
Journal:  ACS Chem Neurosci       Date:  2014-02-27       Impact factor: 4.418

Review 8.  An Emerging Circuit Pharmacology of GABAA Receptors.

Authors:  Elif Engin; Rebecca S Benham; Uwe Rudolph
Journal:  Trends Pharmacol Sci       Date:  2018-06-11       Impact factor: 14.819

9.  Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.

Authors:  Martin H Bolli; Judith Marfurt; Corinna Grisostomi; Christoph Boss; Christoph Binkert; Patrick Hess; Alexander Treiber; Eric Thorin; Keith Morrison; Stephan Buchmann; Daniel Bur; Henri Ramuz; Martine Clozel; Walter Fischli; Thomas Weller
Journal:  J Med Chem       Date:  2004-05-20       Impact factor: 7.446

10.  Optimization of Clonazepam Therapy Adjusted to Patient's CYP3A Status and NAT2 Genotype.

Authors:  Katalin Tóth; Gábor Csukly; Dávid Sirok; Ales Belic; Ádám Kiss; Edit Háfra; Máté Déri; Ádám Menus; István Bitter; Katalin Monostory
Journal:  Int J Neuropsychopharmacol       Date:  2016-12-30       Impact factor: 5.176
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  3 in total

1.  The Potential of Parsley Polyphenols and Their Antioxidant Capacity to Help in the Treatment of Depression and Anxiety: An In Vivo Subacute Study.

Authors:  Imane Es-Safi; Hamza Mechchate; Amal Amaghnouje; Omkulthom Mohamed Al Kamaly; Fatima Zahra Jawhari; Hamada Imtara; Andriy Grafov; Dalila Bousta
Journal:  Molecules       Date:  2021-04-01       Impact factor: 4.411

Review 2.  Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects.

Authors:  Amber N Edinoff; Catherine A Nix; Amira S Odisho; Caroline P Babin; Alyssa G Derouen; Salim C Lutfallah; Elyse M Cornett; Kevin S Murnane; Adam M Kaye; Alan D Kaye
Journal:  Neurol Int       Date:  2022-08-22

3.  Trends and Geographic Variabilities in Benzodiazepines Prescription in Primary Care to Older Adults: A 3-Year Population-Based Ecological Study in Portugal.

Authors:  Ana Bárbara Tavares; Ana Isabel Placido; Daniela Almeida Rodrigues; Manuel Morgado; Adolfo Figueiras; Maria Teresa Herdeiro; Fátima Roque
Journal:  Healthcare (Basel)       Date:  2022-07-19
  3 in total

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