Chunshuang Guan1, Yuxin Shi2, Jinxin Liu3, Yuxin Yang4, Qianqian Zhang5, Zhiyan Lu6, Guangping Zheng7, Wen Ye2, Ming Xue1, Xingang Zhou8, Na Zhang9, Hongjun Li10, Ruming Xie1, Budong Chen1, Puxuan Lu11. 1. Department of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China. 2. Department of Radiology, Shanghai Public Health Clinical Center, Shanghai, China. 3. Department of Radiology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China. 4. Department of Radiology, The Sixth People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China. 5. Department of Radiology, Zhoukou Central Hospital, Zhoukou, China. 6. Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China. 7. Department of Radiology, The Shenzhen No. 3 People's Hospital, Guangdong Medical College, Shenzhen, China. 8. Department of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing, China. 9. Department of Radiology, Chengdu Public Health Clinical Center, Chengdu, China. 10. Department of Radiology, Beijing You'an Hospital, Capital Medical University, Beijing, China. 11. Department of Radiology, Shenzhen Center for Chronic Disease Control, Shenzhen, China.
Abstract
BACKGROUND: Acquired immunodeficiency syndrome-associated Kaposi's sarcoma (AIDS-KS) was the first malignant neoplasm to be described as being related to AIDS. The lungs are the most common visceral site of AIDS-KS. This study aimed to analyze the computed tomography (CT) manifestations of pulmonary involvement in AIDS-KS. METHODS: Twenty-nine male patients were enrolled in this retrospective study. Imaging evaluation parameters included lesion distribution, the flame sign, interlobular septal thickening, peribronchovascular interstitium thickening, ground-glass opacity (GGO), dilated blood vessels in lesions, and pleural effusion. RESULTS: A peribronchovascular distribution was observed in all patients, predominantly in the lower lobes. Of the patients, 58.62% (17/29) exhibited the flame sign, 75.86% (22/29) had interlobular septal thickening, 72.41% (21/29) had peribronchovascular interstitium thickening, 82.76% (24/29) had GGO, and 34.48% (10/29) had pleural effusion. Enlarged lymph nodes with a short-axis diameter >1.0 cm were found in 41.38% (12/29) of the patients. Of the 12 patients who underwent contrast-enhanced CT (CECT), 90.91% (11/12) had dilated blood vessels, and nodules, consolidations, and lymph nodes were observed to be strongly enhanced. Intrapulmonary lesions decreased in size or number after appropriate treatment during follow-up. CONCLUSIONS: Common CT manifestations of pulmonary AIDS-KS include the flame sign, peribronchovascular distribution, peribronchovascular interstitium thickening, interlobular septa thickening, GGO, dilated blood vessel, and strong enhancement of nodules, consolidations, and lymph nodes. It is helpful to follow up the therapeutic effect of pulmonary AIDS-KS by chest CT. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
BACKGROUND: Acquired immunodeficiency syndrome-associated Kaposi's sarcoma (AIDS-KS) was the first malignant neoplasm to be described as being related to AIDS. The lungs are the most common visceral site of AIDS-KS. This study aimed to analyze the computed tomography (CT) manifestations of pulmonary involvement in AIDS-KS. METHODS: Twenty-nine male patients were enrolled in this retrospective study. Imaging evaluation parameters included lesion distribution, the flame sign, interlobular septal thickening, peribronchovascular interstitium thickening, ground-glass opacity (GGO), dilated blood vessels in lesions, and pleural effusion. RESULTS: A peribronchovascular distribution was observed in all patients, predominantly in the lower lobes. Of the patients, 58.62% (17/29) exhibited the flame sign, 75.86% (22/29) had interlobular septal thickening, 72.41% (21/29) had peribronchovascular interstitium thickening, 82.76% (24/29) had GGO, and 34.48% (10/29) had pleural effusion. Enlarged lymph nodes with a short-axis diameter >1.0 cm were found in 41.38% (12/29) of the patients. Of the 12 patients who underwent contrast-enhanced CT (CECT), 90.91% (11/12) had dilated blood vessels, and nodules, consolidations, and lymph nodes were observed to be strongly enhanced. Intrapulmonary lesions decreased in size or number after appropriate treatment during follow-up. CONCLUSIONS: Common CT manifestations of pulmonary AIDS-KS include the flame sign, peribronchovascular distribution, peribronchovascular interstitium thickening, interlobular septa thickening, GGO, dilated blood vessel, and strong enhancement of nodules, consolidations, and lymph nodes. It is helpful to follow up the therapeutic effect of pulmonary AIDS-KS by chest CT. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
Authors: Sara Lodi; Marguerite Guiguet; Dominique Costagliola; Martin Fisher; Andrea de Luca; Kholoud Porter Journal: J Natl Cancer Inst Date: 2010-05-04 Impact factor: 13.506
Authors: J Marcoval; M Bonfill-Ortí; L Martínez-Molina; F Valentí-Medina; R M Penín; O Servitje Journal: Clin Exp Dermatol Date: 2018-06-22 Impact factor: 3.470