Bo Wang1, Congcong Wang1, Fangyi Zhong2, Weiran Pang1, Lili Guo3, Kuan Peng1, Jiaying Xiao1. 1. Department of Biomedical Engineering, Central South University, Changsha, China. 2. Department of Biomedical Engineering, Guangzhou Huaxia Vocational College, Guangzhou, China. 3. Department of Biomedical Engineering, Hunan University, Changsha, China.
Abstract
BACKGROUND: Acoustic resolution-based photoacoustic endoscopy (ARPAE) is a non-invasive potential tool for imaging gastrointestinal and urogenital tracts. However, current ARPAE systems usually only provide 2D sectorial B-mode images, and have the limitation of the image quality significantly deteriorating out-of-focus regions due to transducers with fixed focus in these systems. To overcome these limitations, we put forward a modified back-projection method that can provide 3D images with dynamic focusing in ARPAE. METHODS: A graphics processing unit (GPU)-based parallel computation technique was adopted for efficient computation. Both simulated and phantom/ex-vivo experiments were conducted to validate our method. RESULTS: The findings indicated that our proposed method can effectively improve the lateral resolution and signal-to-noise ratio (SNR) in the out-of-focus regions. For a target 3 mm from the transducer focus, the new method can improve 11 times in the lateral resolution, along with an improvement of up to 37 dB in the SNR. CONCLUSIONS: 3D ARPAE provides high-quality imaging in both focus and out-of-focus regions. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
BACKGROUND: Acoustic resolution-based photoacoustic endoscopy (ARPAE) is a non-invasive potential tool for imaging gastrointestinal and urogenital tracts. However, current ARPAE systems usually only provide 2D sectorial B-mode images, and have the limitation of the image quality significantly deteriorating out-of-focus regions due to transducers with fixed focus in these systems. To overcome these limitations, we put forward a modified back-projection method that can provide 3D images with dynamic focusing in ARPAE. METHODS: A graphics processing unit (GPU)-based parallel computation technique was adopted for efficient computation. Both simulated and phantom/ex-vivo experiments were conducted to validate our method. RESULTS: The findings indicated that our proposed method can effectively improve the lateral resolution and signal-to-noise ratio (SNR) in the out-of-focus regions. For a target 3 mm from the transducer focus, the new method can improve 11 times in the lateral resolution, along with an improvement of up to 37 dB in the SNR. CONCLUSIONS: 3D ARPAE provides high-quality imaging in both focus and out-of-focus regions. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
Entities:
Keywords:
Photoacoustic endoscopy; dynamic focusing; lateral resolution; signal-to-noise ratio
Authors: Joon Mo Yang; Christopher Favazza; Junjie Yao; Ruimin Chen; Qifa Zhou; K Kirk Shung; Lihong V Wang Journal: PLoS One Date: 2015-04-15 Impact factor: 3.240