Literature DB >> 33530557

Purinergic Regulation of Endothelial Barrier Function.

Muhammad Aslam1,2,3, Dursun Gündüz1,4, Christian Troidl1,2,3, Jacqueline Heger5, Christian W Hamm1,2,3, Rainer Schulz5.   

Abstract

Increased vascular permeability is a hallmark of several cardiovascular anomalies, including ischaemia/reperfusion injury and inflammation. During both ischaemia/reperfusion and inflammation, massive amounts of various nucleotides, particularly adenosine 5'-triphosphate (ATP) and adenosine, are released that can induce a plethora of signalling pathways via activation of several purinergic receptors and may affect endothelial barrier properties. The nature of the effects on endothelial barrier function may depend on the prevalence and type of purinergic receptors activated in a particular tissue. In this review, we discuss the influence of the activation of various purinergic receptors and downstream signalling pathways on vascular permeability during pathological conditions.

Entities:  

Keywords:  ADP; ATP; P2X receptors; P2Y receptors; Rac1; RhoA; UTP; adenosine; endothelial permeability; oedema; peripheral actin

Mesh：

Substances：

Year:  2021        PMID： 33530557      PMCID： PMC7865261          DOI： 10.3390/ijms22031207

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  151 in total

1.  Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase.

Authors:  R Beigi; E Kobatake; M Aizawa; G R Dubyak
Journal:  Am J Physiol       Date:  1999-01

2.  Evidence supporting the Nucleotide Axis Hypothesis: ATP release and metabolism by coronary endothelium.

Authors:  I L Buxton; R A Kaiser; B C Oxhorn; D J Cheek
Journal:  Am J Physiol Heart Circ Physiol       Date:  2001-10       Impact factor: 4.733

3.  Activation of adenosine A1 and A2 receptors differentially modulates calcium channels and glycinergic synaptic transmission in rat brainstem.

Authors:  M Umemiya; A J Berger
Journal:  Neuron       Date:  1994-12       Impact factor: 17.173

4.  Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells.

Authors:  Lisa M Schwiebert; William C Rice; Brian A Kudlow; Amanda L Taylor; Erik M Schwiebert
Journal:  Am J Physiol Cell Physiol       Date:  2002-02       Impact factor: 4.249

5.  Thrombin-induced ATP release from human umbilical vein endothelial cells.

Authors:  Stefanie Gödecke; Claudia Roderigo; Christine R Rose; Bernhard H Rauch; Axel Gödecke; Jürgen Schrader
Journal:  Am J Physiol Cell Physiol       Date:  2011-12-07       Impact factor: 4.249

Review 6.  Advances in signalling by extracellular nucleotides. the role and transduction mechanisms of P2Y receptors.

Authors:  D Communi; R Janssens; N Suarez-Huerta; B Robaye; J M Boeynaems
Journal:  Cell Signal       Date:  2000-06       Impact factor: 4.315

Review 7.  The role of adherens junctions and VE-cadherin in the control of vascular permeability.

Authors:  Elisabetta Dejana; Fabrizio Orsenigo; Maria Grazia Lampugnani
Journal:  J Cell Sci       Date:  2008-07-01       Impact factor: 5.285

8.  Adenosine A2 receptors reverse ischemia-reperfusion lung injury independent of beta-receptors.

Authors:  P L Khimenko; T M Moore; L W Hill; P S Wilson; S Coleman; A Rizzo; A E Taylor
Journal:  J Appl Physiol (1985)       Date:  1995-03

9.  Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.

Authors:  M R Blackburn; J B Volmer; J L Thrasher; H Zhong; J R Crosby; J J Lee; R E Kellems
Journal:  J Exp Med       Date:  2000-07-17       Impact factor: 14.307

10.  ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain Barrier In Vitro.

Authors:  Fuxing Yang; Kai Zhao; Xiufeng Zhang; Jun Zhang; Bainan Xu
Journal:  Neural Plast       Date:  2016-10-04       Impact factor: 3.599
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  7 in total

Review 1.  Scrutinizing the Therapeutic Promise of Purinergic Receptors Targeting Depression.

Authors:  Priyanshi Sikka; Tapan Behl; Parteek Chandel; Aayush Sehgal; Sukhbir Singh; Hafiz A Makeen; Mohammed Albratty; Hassan A Alhazmi; Abdulkarim M Meraya
Journal:  Neurotox Res       Date:  2022-08-05       Impact factor: 3.978

Review 2.  Connexin and Pannexin Large-Pore Channels in Microcirculation and Neurovascular Coupling Function.

Authors:  Pía C Burboa; Mariela Puebla; Pablo S Gaete; Walter N Durán; Mauricio A Lillo
Journal:  Int J Mol Sci       Date:  2022-06-30       Impact factor: 6.208

3.  Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model.

Authors:  Ines Sophie Schädlich; Oliver Schnapauff; Lennart Pöls; Jürgen Schrader; Eva Tolosa; Björn Rissiek; Tim Magnus
Journal:  iScience       Date:  2022-05-26

4.  Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells' T helper 17 polarization.

Authors:  Li-Wei Dong; Zhi-Chao Ma; Jiao Fu; Bai-Li Huang; Fu-Jin Liu; Deming Sun; Cheng Lan
Journal:  World J Gastroenterol       Date:  2022-07-07       Impact factor: 5.374

Review 5.  The Role of Pannexin-1 Channels in HIV and NeuroHIV Pathogenesis.

Authors:  Cristian A Hernandez; Eugenin Eliseo
Journal:  Cells       Date:  2022-07-20       Impact factor: 7.666

6.  The impaired distribution of adenosine deaminase isoenzymes in multiple sclerosis plasma and cerebrospinal fluid.

Authors:  Barbara Kutryb-Zajac; Ada Kawecka; Fionä Caratis; Krzysztof Urbanowicz; Alicja Braczko; Tomomi Furihata; Bartosz Karaszewski; Ryszard T Smolenski; Aleksandra Rutkowska
Journal:  Front Mol Neurosci       Date:  2022-09-20       Impact factor: 6.261

7.  The Antiplatelet Action of S-Nitroso Human Serum Albumin in Whole Blood.

Authors:  Melina Tsiountsioura; Gerhard Cvirn; Axel Schlagenhauf; Harald Haidl; Kathrin Zischmeier; Nicole Janschitz; Martin Koestenberger; Willibald Wonisch; Margret Paar; Thomas Wagner; Eva-Christine Weiss; Seth Hallström
Journal:  Biomedicines       Date:  2022-03-11
  7 in total

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