Literature DB >> 33530186

A randomized, controlled, multicenter clinical study of the "improved sitting Wuqinxi" intervention for mechanically ventilated patients in the intensive care unit.

Guojin Xiao1, Jing Liu2, Li Zhang3, Yan Yue3, Xiangwen Weng3, Zilin He3, Lei Lv3, Wendong Dong3, Jing Li3, Kunlan Long3, Ren Yang3.   

Abstract

INTRODUCTION: Mechanical ventilation is a powerful tool for the treatment of various critical emergencies. However, surviving critically ill patients often have poor psychological and physiological outcomes. Prevention of various complications and adverse outcomes of mechanical ventilation is a priority and a challenge in the intensive care unit (ICU). Early intervention is the key to reducing complications and improving outcomes of mechanical ventilation in the ICU. As an auxiliary rehabilitation treatment, the improved sitting Wuqinxi intervention has recognized unique advantages. It has achieved beneficial therapeutic effects during early intervention in clinical practice. It can reduce the incidence of delirium, shorten the duration of mechanical ventilation, and prevent complications and secondary damages related to mechanical ventilation in the ICU. Therefore, the purpose of this study will be to explore the effect of improved sitting Wuqinxi on the clinical outcomes of mechanically ventilated ICU patients.
METHODS: This prospective, multicenter, randomized, single-blinded, parallel controlled clinical study will involve 160 patients who met the inclusion criteria. The patients will be randomly divided into the experimental and control groups. Both groups will be given standardized comprehensive western medicine treatment (including mechanical ventilation) and routine care in the ICU. Management of the experimental group will also include "improved sitting Wuqinxi," with the treatment objective to observe the effect of the improved sitting Wuqinxi intervention on the clinical outcomes in mechanically ventilated ICU patients. The outcome measures will include the incidence of complications, duration of mechanical ventilation, length of ICU stay, and cost of hospitalization. In addition, the effect of the improved sitting Wuqinxi intervention on the safety indexes of mechanically ventilated ICU patients will be assessed and the clinical effects of the improved sitting Wuqinxi intervention will be comprehensively evaluated. DISCUSSION: The purpose of this study will be to evaluate the effect of the improved sitting Wuqinxi intervention on the incidence of complications, duration of mechanical ventilation, length of ICU stay, cost of hospitalization, and safety indicators. If successful, it will provide a reliable, simple, and feasible auxiliary rehabilitation treatment scheme for mechanically ventilated ICU patients.
Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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Year:  2021        PMID: 33530186      PMCID: PMC7850763          DOI: 10.1097/MD.0000000000023898

Source DB:  PubMed          Journal:  Medicine (Baltimore)        ISSN: 0025-7974            Impact factor:   1.817


  17 in total

1.  Critical illness polyneuropathy in multiple organ dysfunction syndrome and weaning from the ventilator.

Authors:  F S Leijten; A W De Weerd; D C Poortvliet; V A De Ridder; C Ulrich; J E Harink-De Weerd
Journal:  Intensive Care Med       Date:  1996-09       Impact factor: 17.440

Review 2.  Muscle wasting and early mobilization in acute respiratory distress syndrome.

Authors:  Christopher J Walsh; Jane Batt; Margaret S Herridge; Claudia C Dos Santos
Journal:  Clin Chest Med       Date:  2014-09-30       Impact factor: 2.878

Review 3.  Weaning from prolonged mechanical ventilation.

Authors:  M L Nevins; S K Epstein
Journal:  Clin Chest Med       Date:  2001-03       Impact factor: 2.878

Review 4.  Mechanical ventilation.

Authors:  M J Tobin
Journal:  N Engl J Med       Date:  1994-04-14       Impact factor: 91.245

5.  Predictors of prolonged weaning and survival during ventilator weaning in a respiratory ICU.

Authors:  Jacobo Sellares; Miquel Ferrer; Esteban Cano; Hugo Loureiro; Mauricio Valencia; Antoni Torres
Journal:  Intensive Care Med       Date:  2011-03-04       Impact factor: 17.440

6.  Early activity is feasible and safe in respiratory failure patients.

Authors:  Polly Bailey; George E Thomsen; Vicki J Spuhler; Robert Blair; James Jewkes; Louise Bezdjian; Kristy Veale; Larissa Rodriquez; Ramona O Hopkins
Journal:  Crit Care Med       Date:  2007-01       Impact factor: 7.598

7.  Morbidity, mortality, and quality-of-life outcomes of patients requiring >or=14 days of mechanical ventilation.

Authors:  Alain Combes; Marie-Alyette Costa; Jean-Louis Trouillet; Jérôme Baudot; Mourad Mokhtari; Claude Gibert; Jean Chastre
Journal:  Crit Care Med       Date:  2003-05       Impact factor: 7.598

8.  Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis.

Authors:  Greet Hermans; Helena Van Mechelen; Beatrix Clerckx; Tine Vanhullebusch; Dieter Mesotten; Alexander Wilmer; Michael P Casaer; Philippe Meersseman; Yves Debaveye; Sophie Van Cromphaut; Pieter J Wouters; Rik Gosselink; Greet Van den Berghe
Journal:  Am J Respir Crit Care Med       Date:  2014-08-15       Impact factor: 21.405

9.  SPIRIT 2013 statement: defining standard protocol items for clinical trials.

Authors:  An-Wen Chan; Jennifer M Tetzlaff; Douglas G Altman; Andreas Laupacis; Peter C Gøtzsche; Karmela Krleža-Jerić; Asbjørn Hróbjartsson; Howard Mann; Kay Dickersin; Jesse A Berlin; Caroline J Doré; Wendy R Parulekar; William S M Summerskill; Trish Groves; Kenneth F Schulz; Harold C Sox; Frank W Rockhold; Drummond Rennie; David Moher
Journal:  Ann Intern Med       Date:  2013-02-05       Impact factor: 25.391

10.  Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit.

Authors:  Nazir I Lone; Timothy S Walsh
Journal:  Crit Care       Date:  2011-03-27       Impact factor: 9.097

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