| Literature DB >> 33528652 |
Anselm B M Fuermaier1, Lara Tucha2,3, Marah Butzbach2, Matthias Weisbrod4,5, Steffen Aschenbrenner4,6, Oliver Tucha2,3,7.
Abstract
Adults diagnosed with attention-deficit/hyperactivity disorder (ADHD) commonly experience impairments in multiple domains of daily living. Work has a central role in daily life and is susceptible to ADHD due to its cognitive demands. The present study seeks to examine the nature of work-related problems and impairments of adults with ADHD, and explores the association to ADHD symptoms and neuropsychological test performance. A community sample of 1231 individuals took part in this study and completed a set of questionnaires assessing ADHD symptoms and work-related problems. Furthermore, a clinical sample of 134 adults diagnosed with ADHD were recruited from an ADHD outpatient clinic, who completed the same set of questionnaires. A subsample of 51 patients with ADHD additionally performed a neuropsychological assessment using tests of attention and executive functions. Work-related problems were found both in individuals of the community sample with symptoms of ADHD and individuals diagnosed with ADHD. Individuals with ADHD reported work related problems particularly in not meeting their own standards and perceived potential, yet it less commonly manifests in negative performance evaluations at work or job loss. ADHD symptoms, in particular symptoms of inattention, were found to be strongly associated with work-related problems, whereas neuropsychological test performance was no meaningful predictor of functioning at work. This study emphasizes the susceptibility of individuals' functioning at work to ADHD symptoms and impairments associated with ADHD. ADHD related difficulties at work should be considered in the clinical evaluation and targeted screening at the work place to provide support when indicated.Entities:
Keywords: ADHD; Daily functioning; Occupational functioning; Real life functioning; Work
Mesh:
Year: 2021 PMID: 33528652 PMCID: PMC8295111 DOI: 10.1007/s00702-021-02309-z
Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN: 0300-9564 Impact factor: 3.850
Community sample characteristics and work status
| Community sample, total sample, ( | Community sample, ADHD index ≥ M + 1SD ( | |
|---|---|---|
| Age (years) | 45.3 ± 14.3 | 43.4 ± 13.6 |
| Gender (% female) | 52.4 | 51.5 |
| Education (years) | 12.5 ± 2.5 | 12.4 ± 2.2 |
| Civil statusa (%) | 23.0/20.6/47.1/7.2/2.1 | 19.7/22.7/51.5/6.1/0 |
| Living situationb (%) | 22.5/55.0/22.5 | 21.0/64.5/14.5 |
| Work statusc (%) | 73.1/4.9/4.0/17.9 | 73.0/0/3.2/23.8 |
| CAARS-S:L—Inattention | 6.7 ± 5.3 | 18.2 ± 5.7 |
| CAARS-S:L—Hyperactivity | 7.7 ± 5.5 | 18.0 ± 6.1 |
| CAARS-S:L—Impulsivity | 7.0 ± 5.6 | 19.3 ± 6.0 |
| CAARS-S:L—ADHD Index | 6.6 ± 5.2 | 19.8 ± 3.8 |
| WFIRS—Work (mean score) | 0.34 ± 0.51 | 1.28 ± 0.86 |
| Item 1 (% ≥ 2) | 5.8 | 37.1 |
| Item 2 (% ≥ 2) | 7.4 | 45.0 |
| Item 3 (% ≥ 2) | 7.6 | 52.8 |
| Item 4 (% ≥ 2) | 7.1 | 52.8 |
| Item 5 (% ≥ 2) | 5.1 | 48.0 |
| Item 6 (% ≥ 2) | 5.8 | 39.3 |
| Item 7 (% ≥ 2) | 5.2 | 39.7 |
| Item 8 (% ≥ 2) | 5.2 | 37.0 |
| Item 9 (% ≥ 2) | 5.1 | 43.6 |
| Item 10 (% ≥ 2) | 9.3 | 48.2 |
| Item 11 (% ≥ 2) | 4.8 | 51.0 |
CAARS Conners’ Adult ADHD Rating Scale, WFIRS Weiss Functional Impairment Rating Scale
aSingle/in partnership/married/divorced/widowed
bAlone/with one more person/with more than one more person
cIn paid work/in training or education/pensioned/unemployed
Characteristics of individuals diagnosed with ADHD (total patient sample, n = 134) and the community comparison group (n = 268)
| Individuals with ADHD ( | Community comparison group ( | |||
|---|---|---|---|---|
| Age (years) | 34.1 ± 11.7 | 34.2 ± 11.3 | − 0.082 (399) | 0.935 |
| Gender (% female) | 35.1 | 39.0 | 0.493 (1) | 0.483 |
| Education (years) | 12.2 ± 2.3 | 12.5 ± 2.4 | − 1.046 (399) | 0.296 |
| ADHD symptom presentationa | 51/2/67/14 | – | – | – |
| Comorbidityb | 62/24/9/8/2/2/2/1/1/1 | – | – | – |
| Stimulant drug treatment (%yes) | 10.4 | – | – | – |
| Work statusc | 55.3/27.3/1.5/15.9 | 73.9/13.6/0/12.5 | 18.229 (3) | < 0.001* |
| CAARS-S:L—Inattention | 22.3 ± 6.7 | 7.5 ± 6.0 | 21.561 (399) | < 0.001* |
| CAARS-S:L—Hyperactivity | 18.3 ± 7.4 | 8.8 ± 6.2 | 12.737 (399) | < 0.001* |
| CAARS-S:L – Impulsivity | 19.7 ± 7.9 | 7.9 ± 6.8 | 14.698 (399) | < 0.001* |
| CAARS-S:L – ADHD Index | 21.7 ± 6.2 | 7.5 ± 5.9 | 21.967 (399) | < 0.001* |
| WFIRS – Work (mean score) | 1.24 ± 0.68 | 0.50 ± 0.62 | 10.258 (374) | < 0.001* |
| Item 1 (% ≥ 2) | 42.1 | 8.7 | 58.000 (1) | < 0.001* |
| Item 2 (% ≥ 2) | 55.0 | 11.7 | 79.195 (1) | < 0.001* |
| Item 3 (% ≥ 2) | 26.3 | 12.3 | 10.792 (1) | 0.001* |
| Item 4 (% ≥ 2) | 31.1 | 13.2 | 15.091 (1) | < 0.001* |
| Item 5 (% ≥ 2) | 20.0 | 11.4 | 4.325 (1) | 0.038 |
| Item 6 (% ≥ 2) | 30.8 | 11.5 | 20.014 (1) | < 0.001* |
| Item 7 (% ≥ 2) | 23.2 | 9.3 | 12.751 (1) | < 0.001* |
| Item 8 (% ≥ 2) | 27.8 | 7.8 | 25.577 (1) | < 0.001* |
| Item 9 (% ≥ 2) | 40.7 | 9.7 | 48.627 (1) | < 0.001* |
| Item 10 (% ≥ 2) | 69.2 | 16.6 | 99.759 (1) | < 0.001* |
| Item 11 (% ≥ 2) | 22.5 | 9.4 | 10.586 (1) | 0.001* |
CAARS Conners’ Adult ADHD Rating Scale, WFIRS Weiss Functional Impairment Rating Scale
*Significant at p < 0.01
aInattentive presentation/hyperactive-impulsive presentation/combined presentation/not reported
bNumber of patients affected with one or more comorbid psychiatric disorders: Mood disorder/anxiety disorder/personality disorder/substance abuse/psychotic disorder/somatoform disorder/autism/eating disorder/sleep disorder/low intelligence
cIn paid work/in training or education/pensioned/unemployed
WFIRS Work subscale
| Item number | Item |
|---|---|
| #1 | Problems performing required duties |
| #2 | Problems with getting your work done efficiently |
| #3 | Problems with your supervisor |
| #4 | Problems keeping a job |
| #5 | Getting fired from work |
| #6 | Problems working in a team |
| #7 | Problems with your attendance |
| #8 | Problems with being late |
| #9 | Problems taking on new tasks |
| #10 | Problems working to your potential |
| #11 | Poor performance evaluations |
WFIRS Weiss Functional Impairment Rating Scale
Answers options include 0 (never), 1 (sometimes), 2 (often), 3 (very often), or ‘not applicable’
Cognitive performance scores and bivariate associations to WFIRS Work score in a subsample of patients with ADHD (n = 51)
| Cognitive functions with test variables | Min | Max | Mean | SD | % PR ≤ 16 | Correlation ( |
|---|---|---|---|---|---|---|
| Selective attention | ||||||
| WAFS—RT (ms) | 215 | 600 | 404 | 95 | 36.0 | 0.08 |
| WAFS—SD | 1.10 | 1.48 | 1.26 | 0.09 | 39.2 | < 0.01 |
| WAFS—Omissions | 0 | 10 | 1.16 | 2.04 | 37.3 | 0.13 |
| WAFS—Commissions | 0 | 26 | 4.57 | 4.96 | 29.4 | 0.01 |
| Vigilance | ||||||
| WAFV—RT (ms) | 229 | 656 | 441 | 83 | 14.0 | 0.21 |
| WAFV—SD | 1.14 | 3.48 | 1.30 | 0.33 | 25.5 | 0.17 |
| WAFV—Omissions | 0 | 20 | 2.14 | 3.66 | 37.3 | 0.09 |
| WAFV—Commissions | 0 | 27 | 3.20 | 4.95 | 33.3 | 0.10 |
| Cognitive flexibility | ||||||
| TMT-A—Time (s) | 11.2 | 40.6 | 18.6 | 5.2 | 24.0 | 0.15 |
| TMT-B—Time (s) | 13.2 | 82.8 | 34.0 | 13.5 | 32.0 | 0.03 |
| Verbal fluency | ||||||
| RWT—Produced words | 7 | 26 | 15.96 | 4.46 | 44 | – 0.01 |
| Working memory | ||||||
| NBV—Correct responses | 3 | 15 | 11.14 | 2.99 | 24.5 | – 0.11 |
| Planning | ||||||
| TOL-F—Planning score | 6 | 20 | 14.81 | 3.07 | 22.9 | – 0.10 |
WAFS perception and attention functions—selective attention, WAFV perception and attention functions—vigilance, TMT trail making test, RWT regensburg word fluency test, NBV N-back Verbal, TOL-F tower of London—Freiburger Version
* None of the correlations met statistical significance level p < 0.01 (all p’s ≥ 0.148)
Fig. 1Comparison of the proportion of individuals indicating impairment (score ≥ 2) in each of the WFIRS Work item between patients with ADHD (n = 134) and the community comparison group (n = 268)
Cumulative percentages of the number of Work impairments of patients with ADHD (n = 134) and the community comparison group (n = 268)
| Number of | Patients with ADHD ( | Community comparison group ( |
|---|---|---|
| 0 | 19.4 | 72.4 |
| 1 | 31.3 | 82.8 |
| 2 | 44.8 | 85.1 |
| 3 | 59.7 | 88.4 |
| 4 | 70.1 | 90.7 |
| 5 | 79.1 | 91.8 |
| 6 | 84.3 | 92.9 |
| 7 | 90.3 | 94.0 |
| 8 | 93.3 | 96.3 |
| 9 | 96.3 | 97.4 |
| 10 | 99.3 | 98.9 |
| 11 | 100 | 100 |
Pearson correlation analyses (r, p) between WFIRS Work score and ADHD symptoms in different subsets of the community sample and patients with ADHD
| WFIRS | ||||
|---|---|---|---|---|
| Community sample, total sample, ( | Community sample, ADHD index ≥ M + 1SD ( | Community sample, comparison group ( | Individuals with ADHD ( | |
| CAARS-S:L—Inattention | 0.596, < 0.001* | 0.467, < 0.001* | 0.577, < 0.001* | 0.397, < 0.001* |
| CAARS-S:L—Hyperactivity | 0.415, < 0.001* | 0.310, 0.014 | 0.437, < 0.001* | 0.229, 0.011 |
| CAARS-S:L—Impulsivity | 0.519, < 0.001* | 0.375, 0.003* | 0.534, < 0.001* | 0.345, < 0.001* |
| CAARS-S:L—ADHD Index | 0.569, < 0.001* | 0.294, 0.020 | 0.575, < 0.001* | 0.462, < 0.001* |
CAARS Conners’ Adult ADHD Rating Scale, WFIRS Weiss Functional Impairment Rating Scale
*Significant at p < 0.01