Literature DB >> 33527064

Relationship Between Degeneration or Sagittal Balance With Modic Changes in the Cervical Spine.

Serkan Kitiş1, Serdar Çevik2,3, Atilla Kaplan4, Hakan Yılmaz5, Salim Katar6, Serhat Cömert7, Ülkün Ünsal8.   

Abstract

OBJECTIVE: This study evaluates the relationship between degenerative and Modic changes (MCs) in the cervical spine and compares the results with the cervical sagittal balance parameters.
METHODS: We retrospectively reviewed 275 patients with neck pain who applied to our outpatient clinic and underwent cervical magnetic resonance imaging (MRI) and cervical anteroposterior (AP)/lateral (Lat) X-ray radiography between January 2016 and January 2018. The clinics, demographic information, and radiological findings of the patients were examined. Modic changes, disc degeneration, and facet degeneration (FD) were examined by cervical MRI, and T1 slope and Cobb angle were measured by cervical AP/Lat X-ray radiography. These results were compared to evaluate their relations with each other.
RESULTS: No relationship between the presence or absence of degenerative changes (Modic changes, facet degeneration, and disc degeneration) and sagittal balance parameters (T1 slope and Cobb angle) was found. However, when each cervical segment was examined separately, facet degeneration at the C4-C5 level and Modic changes at the C3-C4, C4-C5, and C6-C7 levels were statistically significant with the Cobb angles, and the Modic changes at the C3-C4 level and disc degeneration at the C2-C3 level were found to be significant with T1 slope values.
CONCLUSIONS: Our findings indicate that MCs increased with decreased cervical curvature, increasing disc and facet degeneration, although the causal mechanisms are not clear.
Copyright © 2021, Kitiş et al.

Entities:  

Keywords:  cervical spine; cobb angle; disc degeneration; facet degeneration; magnetic resonance imaging; modic changes; t1 slope

Year:  2021        PMID: 33527064      PMCID: PMC7842237          DOI: 10.7759/cureus.12949

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  23 in total

1.  Multidimensional vertebral endplate defects are associated with disc degeneration, modic changes, facet joint abnormalities, and pain.

Authors:  Uruj Zehra; Jason Pui Yin Cheung; Cora Bow; William Lu; Dino Samartzis
Journal:  J Orthop Res       Date:  2019-03-28       Impact factor: 3.494

2.  Analysis of the sagittal balance of the spine and pelvis using shape and orientation parameters.

Authors:  Eric Berthonnaud; Joannès Dimnet; Pierre Roussouly; Hubert Labelle
Journal:  J Spinal Disord Tech       Date:  2005-02

3.  Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging.

Authors:  M T Modic; P M Steinberg; J S Ross; T J Masaryk; J R Carter
Journal:  Radiology       Date:  1988-01       Impact factor: 11.105

4.  Do Modic changes affect cervical sagittal alignment and motion in symptomatic patients?

Authors:  Tong Tong; Xian-Da Gao; Jia Li; Jing-Tao Zhang; Rui-Jie Niu; Zhao Liu; Yong Shen
Journal:  Eur Spine J       Date:  2017-04-18       Impact factor: 3.134

Review 5.  Imaging of degenerative disk disease.

Authors:  M T Modic; T J Masaryk; J S Ross; J R Carter
Journal:  Radiology       Date:  1988-07       Impact factor: 11.105

6.  Modic changes in the cervical spine: prospective 10-year follow-up study in asymptomatic subjects.

Authors:  M Matsumoto; E Okada; D Ichihara; K Chiba; Y Toyama; H Fujiwara; S Momoshima; Y Nishiwaki; T Takahata
Journal:  J Bone Joint Surg Br       Date:  2012-05

7.  Effect of Modic changes on spinal canal stenosis and segmental motion in cervical spine.

Authors:  Tetsuo Hayashi; Michael D Daubs; Akinobu Suzuki; Kevin Phan; Keiichiro Shiba; Jeffrey C Wang
Journal:  Eur Spine J       Date:  2014-06-10       Impact factor: 3.134

8.  Kinematic analysis of the relationship between Modic changes and sagittal balance parameters in the cervical spine.

Authors:  Zikun Ma; Peng Liu; Jingpei Liu; Jianhui Mou; Zhaolin Wang; Dong Sun; Jie Cheng; Dengwei Zhang; Jianlin Xiao
Journal:  Medicine (Baltimore)       Date:  2017-08       Impact factor: 1.889

9.  Relationship Between Modic Changes and Sagittal Balance Parameters in the Cervical Spine.

Authors:  Jian-Ping Wu; Quan-Bin Wang; Xiao-Jun Feng; Qiang Wang; Mao-Hua Cheng
Journal:  Med Sci Monit       Date:  2018-09-02

10.  Characteristics of Modic changes in cervical kyphosis and their association with axial neck pain.

Authors:  Yonghui An; Jia Li; Yongqian Li; Yong Shen
Journal:  J Pain Res       Date:  2017-07-14       Impact factor: 3.133

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