| Literature DB >> 33527061 |
Ibrahim Sange1, Mohamed Wael F Mohamed2, Su Aung3,4, Nakul Mereddy4, Pousette Hamid5.
Abstract
Gluten-sensitive enteropathy or Celiac disease (CD) is a disease that has become very prevalent in most parts of the globe especially in the western world. Resulting from a chaotic interplay between the backgrounds of autoimmunity and genetics, this disorder targets primarily the gastrointestinal tract with ominous extraintestinal counterparts that have a very discrete presentation. Among those counterparts, the one that has been reviewed in this article is the involvement of the endocrine system as concurrence of hormonal disorders with CD possesses numerous challenges that lead to a refractory treatment and a dull prognosis. This review article aims to feature the effect of the CD and endocrine disorders on one another, especially if either of the diseases is asymptomatic, explore the clinical dilemma faced by clinicians in various specialties, and, hence, further pave a path into the importance of rigorous screening and diagnosis.Entities:
Keywords: celiac disease; celiac disease and autoimmunity; celiac disease and diabetes; celiac disease and endocrine system; celiac disease and glandular autoimmunity; celiac disease and thyroid
Year: 2020 PMID: 33527061 PMCID: PMC7842251 DOI: 10.7759/cureus.12383
Source DB: PubMed Journal: Cureus ISSN: 2168-8184