Literature DB >> 33527045

Live Bacteria Supplementation as Probiotic for Managing Fishy, Odorous Vaginal Discharge Disease of Bacterial Vaginosis: An Alternative Treatment Option?

Lubna Mohammed1, Moiz Javed1, Aldanah Althwanay1, Farah Ahsan1, Federico Oliveri2, Harshit K Goud3, Zainab Mehkari1, Ian H Rutkofsky4.   

Abstract

Bacterial vaginosis (BV) is a universally prevalent cause of genital discomfort in females belonging to the reproductive age group, rendering the vagina more susceptible to various other complications. The standard treatment of BV involves using metronidazole and clindamycin, which help eliminate the infection but play no role in re-flourishing the normal vaginal homeostasis, which is lactobacilli preponderant, thereby rendering the vagina more prone to re-infection. Hence, clinical research has been performed to increase vaginal lactobacillus count through oral or vaginal supplementation. This current study's main objective is to review the previously conducted research regarding the efficiency of probiotic supplementation in the prevention and treatment of BV.
Copyright © 2020, Mohammed et al.

Entities:  

Keywords:  bacterial vaginosis; gardenella; lactobacillus; live bacteria; probiotics; probiotics for vagina; probiotics in bacterial vaginosis; recurrent bacterial vaginosis; vaginal health; vaginal infections

Year:  2020        PMID: 33527045      PMCID: PMC7842843          DOI: 10.7759/cureus.12362

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  33 in total

1.  Efficacy of vaginal probiotic capsules for recurrent bacterial vaginosis: a double-blind, randomized, placebo-controlled study.

Authors:  Wang Ya; Cheryl Reifer; Larry E Miller
Journal:  Am J Obstet Gynecol       Date:  2010-08       Impact factor: 8.661

2.  Randomized, placebo-controlled phase 2 trial of a Lactobacillus crispatus probiotic given intravaginally for prevention of recurrent urinary tract infection.

Authors:  Ann E Stapleton; Melissa Au-Yeung; Thomas M Hooton; David N Fredricks; Pacita L Roberts; Christopher A Czaja; Yuliya Yarova-Yarovaya; Tina Fiedler; Marsha Cox; Walter E Stamm
Journal:  Clin Infect Dis       Date:  2011-04-14       Impact factor: 9.079

3.  Molecular identification of vaginal lactobacilli isolated from Bulgarian women.

Authors:  Galina D Stoyancheva; Svetla T Danova; Ivo Y Boudakov
Journal:  Antonie Van Leeuwenhoek       Date:  2006-07-27       Impact factor: 2.271

4.  A cluster analysis of bacterial vaginosis-associated microflora and pelvic inflammatory disease.

Authors:  Roberta B Ness; Kevin E Kip; Sharon L Hillier; David E Soper; Carol A Stamm; Richard L Sweet; Peter Rice; Holly E Richter
Journal:  Am J Epidemiol       Date:  2005-08-10       Impact factor: 4.897

Review 5.  Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma.

Authors:  P G Larsson; M Bergström; U Forsum; B Jacobsson; A Strand; P Wölner-Hanssen
Journal:  APMIS       Date:  2005-04       Impact factor: 3.205

Review 6.  The changing landscape of the vaginal microbiome.

Authors:  Bernice Huang; Jennifer M Fettweis; J Paul Brooks; Kimberly K Jefferson; Gregory A Buck
Journal:  Clin Lab Med       Date:  2014-09-15       Impact factor: 1.935

Review 7.  The Human Microbiome during Bacterial Vaginosis.

Authors:  Andrew B Onderdonk; Mary L Delaney; Raina N Fichorova
Journal:  Clin Microbiol Rev       Date:  2016-04       Impact factor: 26.132

8.  Comparison of Amsel criteria, Nugent score, culture and two CE-IVD marked quantitative real-time PCRs with microbiota analysis for the diagnosis of bacterial vaginosis.

Authors:  Ellen H A van den Munckhof; Rosalie L van Sitter; Kim E Boers; Ronald F Lamont; René Te Witt; Saskia le Cessie; Cornelis W Knetsch; Leen-Jan van Doorn; Wim G V Quint; Anco Molijn; Maurine A Leverstein-van Hall
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2019-03-22       Impact factor: 3.267

Review 9.  Probiotics in the Prevention and Treatment of Postmenopausal Vaginal Infections: Review Article.

Authors:  Jun-Mo Kim; Yoo Jin Park
Journal:  J Menopausal Med       Date:  2017-12-29

10.  Supplementation of standard antibiotic therapy with oral probiotics for bacterial vaginosis and aerobic vaginitis: a randomised, double-blind, placebo-controlled trial.

Authors:  Piotr B Heczko; Anna Tomusiak; Paweł Adamski; Artur J Jakimiuk; Grzegorz Stefański; Aleksandra Mikołajczyk-Cichońska; Magdalena Suda-Szczurek; Magdalena Strus
Journal:  BMC Womens Health       Date:  2015-12-03       Impact factor: 2.809

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