Literature DB >> 33526110

Medical cannabis use in the United States: a retrospective database study.

V Kishan Mahabir1, Jamil J Merchant1, Christopher Smith2, Alisha Garibaldi1.   

Abstract

INTRODUCTION: Growing interest in the medicinal properties of cannabis has led to an increase in its use to treat medical conditions, and the establishment of state-specific medical cannabis programs. Despite medical cannabis being legal in 33 states and the District of Colombia, there remains a paucity of data characterizing the patients accessing medical cannabis programs.
METHODS: We retrospectively reviewed a registry with data from 33 medical cannabis evaluation clinics in the United States, owned and operated by CB2 Insights. Data were collected primarily by face-to-face interviews for patients seeking medical cannabis certification between November 18, 2018 and March 18, 2020. Patients were removed from the analysis if they did not have a valid date of birth, were less than 18, or did not have a primary medical condition reported; a total of 61,379 patients were included in the analysis. Data were summarized using descriptive statistics expressed as a mean (standard deviation (SD)) or median (interquartile range (IQR)) as appropriate for continuous variables, and number (percent) for categorical variables. Statistical tests performed across groups included t-tests, chi-squared tests and regression.
RESULTS: The average age of patients was 45.5, 54.8% were male and the majority were Caucasian (87.5%). Female patients were significantly older than males (47.0 compared to 44.6). Most patients reported cannabis experience prior to seeking medical certification (66.9%). The top three mutually exclusive primary medical conditions reported were unspecified chronic pain (38.8%), anxiety (13.5%) and post-traumatic stress disorder (PTSD) (8.4%). The average number of comorbid conditions reported was 2.7, of which anxiety was the most common (28.3%). Females reported significantly more comorbid conditions than males (3.1 compared to 2.3).
CONCLUSION: This retrospective study highlighted the range and number of conditions for which patients in the US seek medical cannabis. Rigorous clinical trials investigating the use of medical cannabis to treat pain conditions, anxiety, insomnia, depression and PTSD would benefit a large number of patients, many of whom use medical cannabis to treat multiple conditions.

Entities:  

Keywords:  Anxiety; Chronic pain; Gender; Medical cannabis; Post-traumatic stress disorder

Year:  2020        PMID: 33526110      PMCID: PMC7819290          DOI: 10.1186/s42238-020-00038-w

Source DB:  PubMed          Journal:  J Cannabis Res        ISSN: 2522-5782


  19 in total

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2.  Self-reported cannabis use characteristics, patterns and helpfulness among medical cannabis users.

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Review 3.  A Brief Background on Cannabis: From Plant to Medical Indications.

Authors:  Linda E Klumpers; David L Thacker
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Review 4.  Patient-reported use of medical cannabis for pain, anxiety, and depression symptoms: Systematic review and meta-analysis.

Authors:  Jesse D Kosiba; Stephen A Maisto; Joseph W Ditre
Journal:  Soc Sci Med       Date:  2019-06-08       Impact factor: 4.634

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Journal:  Annu Rev Clin Psychol       Date:  2017-05-08       Impact factor: 18.561

6.  Trends in registered medical marijuana participation across 13 US states and District of Columbia.

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7.  Medical Marijuana Users are More Likely to Use Prescription Drugs Medically and Nonmedically.

Authors:  Theodore L Caputi; Keith Humphreys
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8.  Do women 'over-report' morbidity? Men's and women's responses to structured prompting on a standard question on long standing illness.

Authors:  S Macintyre; G Ford; K Hunt
Journal:  Soc Sci Med       Date:  1999-01       Impact factor: 4.634

Review 9.  Medical Use of Cannabinoids.

Authors:  Ana Isabel Fraguas-Sánchez; Ana Isabel Torres-Suárez
Journal:  Drugs       Date:  2018-11       Impact factor: 9.546

10.  Representation of people with comorbidity and multimorbidity in clinical trials of novel drug therapies: an individual-level participant data analysis.

Authors:  Peter Hanlon; Laurie Hannigan; Jesus Rodriguez-Perez; Colin Fischbacher; Nicky J Welton; Sofia Dias; Frances S Mair; Bruce Guthrie; Sarah Wild; David A McAllister
Journal:  BMC Med       Date:  2019-11-12       Impact factor: 8.775

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  4 in total

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Authors:  Jonathan Ross; Deepika E Slawek; Chenshu Zhang; Joanna L Starrels; Frances R Levin; Nancy L Sohler; Haruka Minami; Julia H Arnsten; Chinazo O Cunningham
Journal:  Pain Med       Date:  2021-12-11       Impact factor: 3.637

2.  Increasing Access to Safe Medical Cannabis: Establishment of a Medical Cannabis Program in a Safety-Net Academic Medical Center.

Authors:  Jonathan Ross; Jaclyn Yamada; Deepika Slawek; Joanna L Starrels; Chinazo O Cunningham; Julia H Arnsten
Journal:  NEJM Catal Innov Care Deliv       Date:  2022-01-19

3.  Developing a real-world evidence base for prescribed cannabis in the United Kingdom: preliminary findings from Project Twenty21.

Authors:  C Sakal; M Lynskey; A K Schlag; D J Nutt
Journal:  Psychopharmacology (Berl)       Date:  2021-05-10       Impact factor: 4.530

4.  Comparing medical cannabis use in 5 US states: a retrospective database study.

Authors:  V Kishan Mahabir; Christopher S Smith; Christopher Vannabouathong; Jamil J Merchant; Alisha L Garibaldi
Journal:  J Cannabis Res       Date:  2021-05-27
  4 in total

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