Literature DB >> 33524384

Nanotechnology as a tool for detection and treatment of arbovirus infections.

Jonatas Lobato Duarte1, Leonardo Delello Di Filippo1, Victor Hugo Sousa Araujo1, Anna Eliza Maciel de Faria Mota Oliveira2, Jennifer Thayanne Cavalcante de Araújo1, Flávia Benini da Rocha Silva1, Mara Cristina Pinto1, Marlus Chorilli3.   

Abstract

Arboviruses are medically important viruses that cause high rates of infection all over the world. In addition, the severity of the symptoms and the inadequate diagnostic methods represent a challenge far beyond eradicating the vector. The lack of specific treatments for arbovirus infections reflects the imminent need for new research for safe and efficient medicines to treat these infections. Nanotechnology is an innovative approach currently used as a platform for developing new treatments, thus improving the biopharmaceutical properties of drugs. It can also be applied to the development of diagnostic devices, improving their detection capacity. The purpose of this paper is to review recent research on the use of nanotechnology for developing new treatments and detection devices for arbovirus infections. Interestingly, it was found that only a few studies report on the use of nanotechnology to treat arbovirus infections and that most of these reports focus on the fabrication of diagnostic tools. Also, some papers report on the use of nanotechnology for the development of vaccines, which in association with mosquito eradication programs could effectively reduce the high rates of infections by these viruses.
Copyright © 2021. Published by Elsevier B.V.

Entities:  

Keywords:  Chikungunya; Dengue; Diagnostics devices; Drug delivery systems; Metallic nanoparticles; Vaccine; Zika

Mesh:

Substances:

Year:  2021        PMID: 33524384     DOI: 10.1016/j.actatropica.2021.105848

Source DB:  PubMed          Journal:  Acta Trop        ISSN: 0001-706X            Impact factor:   3.112


  2 in total

Review 1.  Interventions for the Prevention and Treatment of Japanese Encephalitis.

Authors:  Rohan Chand Sahu; Teeja Suthar; Anchal Pathak; Keerti Jain
Journal:  Curr Infect Dis Rep       Date:  2022-09-23       Impact factor: 3.663

2.  Promoting Responsible Research and Innovation (RRI) During Brazilian Activities of Genomic and Epidemiological Surveillance of Arboviruses.

Authors:  Marta Giovanetti; Luiz Carlos Junior Alcantara; Alfredo Souza Dorea; Qesya Rodrigues Ferreira; Willian de Almeida Marques; Jose Junior Franca de Barros; Talita Emile Ribeiro Adelino; Stephane Tosta; Hegger Fritsch; Felipe Campos de Melo Iani; Maria Angélica Mares-Guia; Alvaro Salgado; Vagner Fonseca; Joilson Xavier; Elisson Nogueira Lopes; Gilson Carlos Soares; Maria Fernanda de Castro Amarante; Vasco Azevedo; Alícia Kruger; Gustavo Correa Matta; Laisa Liane Paineiras-Domingos; Claudia Colonnello; Ana Maria Bispo de Filippis; Carla Montesano; Vittorio Colizzi; Fernanda Khouri Barreto
Journal:  Front Public Health       Date:  2021-07-01
  2 in total

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