Makoto Ikeya1, Yayoi Toyooka1, Mototsugu Eiraku2,3. 1. Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan. 2. Laboratory of Developmental Systems, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan. 3. Institute for Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan.