Lagan Paul1, Tanya Jain2, Manisha Agarwal2, Shalini Singh2. 1. Vitreo-retina Department, Dr. Shroff's Charity Eye Hospital, 5027, Kedarnath Road, Daryaganj, New Delhi, 110002, India. laganpaul@gmail.com. 2. Vitreo-retina Department, Dr. Shroff's Charity Eye Hospital, 5027, Kedarnath Road, Daryaganj, New Delhi, 110002, India.
Abstract
BACKGROUND: Subacute sclerosing panencephalitis (SSPE) is a potentially lethal complication of measles infection. Neurological complications take years to manifest after primary viral infection of brain and can lead to blindness in some individuals. FINDINGS: A 13-year-old female patient with history of Bell's palsy 2 months prior, presented with rapidly progressing necrotizing retinitis in both eyes. Soon after, she was unable to walk, developed myoclonic jerks, altered sensorium and loss of bowel and bladder control. Her clinical history, CSF IgG measles antibody analysis, MRI brain and EEG findings confirmed the diagnosis of SSPE. CONCLUSION: SSPE in our case presented as Bell's palsy and sudden painless diminution of vision due to ocular involvement, and developed full blown disease within 2 months. SSPE can present as a diagnostic challenge and warrants early identification and referral for timely diagnosis and management.
BACKGROUND: Subacute sclerosing panencephalitis (SSPE) is a potentially lethal complication of measlesinfection. Neurological complications take years to manifest after primary viral infection of brain and can lead to blindness in some individuals. FINDINGS: A 13-year-old female patient with history of Bell's palsy 2 months prior, presented with rapidly progressing necrotizing retinitis in both eyes. Soon after, she was unable to walk, developed myoclonic jerks, altered sensorium and loss of bowel and bladder control. Her clinical history, CSF IgG measles antibody analysis, MRI brain and EEG findings confirmed the diagnosis of SSPE. CONCLUSION:SSPE in our case presented as Bell's palsy and sudden painless diminution of vision due to ocular involvement, and developed full blown disease within 2 months. SSPE can present as a diagnostic challenge and warrants early identification and referral for timely diagnosis and management.
Authors: A Serdaroğlu; K Gücüyener; I Dursun; K Aydin; C Okuyaz; M Subaşi; M Or; B Ozkan Journal: Ocul Immunol Inflamm Date: 2005 Sep-Oct Impact factor: 3.070