Susan L Murphy1,2, Donnamarie Krause1, Shawn C Roll3, Girish Gandikota4, Mary Barber1, Dinesh Khanna5. 1. Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA. 2. VA Ann Arbor Health Care System, Ann Arbor, MI, Geriatric Research Education and Clinical Center (GRECC). 3. Chan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA. 4. Department of Radiology, University of Michigan, Ann Arbor, MI. 5. Rheumatology Division, Department of Internal Medicine, University of Michigan, Ann Arbor, MI.
Abstract
OBJECTIVES: This study developed a musculoskeletal ultrasound (MSUS) protocol to evaluate rehabilitation outcomes in systemic sclerosis. MATERIALS & METHODS: Three MSUS methods (grey scale, Doppler, strain elastography) and two acquisition techniques (long versus short axis; transducer on skin versus floating on gel) were examined in the forearm before and after rehabilitation treatment. For grey-scale, tissue thickness measures, intra- and inter-rater reliability were calculated (ICCs), and paired t-tests examined differences among techniques. RESULTS: Five people with diffuse cutaneous systemic sclerosis participated. The most valid and reliable grey-scale technique was with the transducer in long-axis, floating on gel. Doppler and strain elastography did not detect changes. Both dermal and subcutaneous thickness measurement error was small; intra- and inter-rater reliability was good to excellent. Preliminary data indicate that treatment may lead to dermal thinning. CONCLUSION: A replicable protocol was established and may be an adjunct to rehabilitation outcome measurement in systemic sclerosis.
OBJECTIVES: This study developed a musculoskeletal ultrasound (MSUS) protocol to evaluate rehabilitation outcomes in systemic sclerosis. MATERIALS & METHODS: Three MSUS methods (grey scale, Doppler, strain elastography) and two acquisition techniques (long versus short axis; transducer on skin versus floating on gel) were examined in the forearm before and after rehabilitation treatment. For grey-scale, tissue thickness measures, intra- and inter-rater reliability were calculated (ICCs), and paired t-tests examined differences among techniques. RESULTS: Five people with diffuse cutaneous systemic sclerosis participated. The most valid and reliable grey-scale technique was with the transducer in long-axis, floating on gel. Doppler and strain elastography did not detect changes. Both dermal and subcutaneous thickness measurement error was small; intra- and inter-rater reliability was good to excellent. Preliminary data indicate that treatment may lead to dermal thinning. CONCLUSION: A replicable protocol was established and may be an adjunct to rehabilitation outcome measurement in systemic sclerosis.
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