Floriane Jochum1, Gabrielle Aubry2, Madeleine Pellerin3, Camille Billard3, Emilie Faller3, Thomas Boisrame3, Lise Lecointre3,4,5, Cherif Akladios3. 1. Department of Gynecology, Strasbourg University Hospital, Strasbourg, France; floriane.jochum@chru-strasbourg.fr. 2. Assistance Publique des Hôpitaux de Paris (AP-HP), Department of Gynecological and Breast Surgery and Oncology, Pitié-Salpêtrière University Hospital, Paris, France. 3. Department of Gynecology, Strasbourg University Hospital, Strasbourg, France. 4. I-Cube UMR 7357 - Laboratoire des Sciences de L'ingénieur, de L'informatique et de L'imagerie. Université de Strasbourg, Strasbourg, France. 5. Institut Hospitalo-Universitaire (IHU), Institute for Minimally Invasive Hybrid Image-Guided Surgery, Université de Strasbourg, Strasbourg, France.
Abstract
BACKGROUND/AIM: This study aimed to evaluate the relevance of laparoscopy in comparison with laparotomy in the management of ovarian cancer in well-selected patients. PATIENTS AND METHODS: Data of consecutive ovarian cancer patients treated by laparoscopy were matched 1:1 to a cohort of patients operated by laparotomy using a propensity score matching. The inclusion criteria included patients who underwent a complete staging procedure in the early stages and optimal upfront or interval debulking surgery for advanced ovarian cancer. RESULTS: In total, 153 patients were included. Propensity score matching led to the analysis of 41 well-balanced pairs of patients. For a median follow-up of 34.0 [19.0-64.0] months and 38.0 [24.5-75.0] months, respectively, no difference was found between the two groups in regards to overall survival (p=0.28) and disease-free survival (p=0.89). CONCLUSION: In well-selected patients, laparoscopic surgery may be a safe and effective alternative to laparotomy.
BACKGROUND/AIM: This study aimed to evaluate the relevance of laparoscopy in comparison with laparotomy in the management of ovarian cancer in well-selected patients. PATIENTS AND METHODS: Data of consecutive ovarian cancerpatients treated by laparoscopy were matched 1:1 to a cohort of patients operated by laparotomy using a propensity score matching. The inclusion criteria included patients who underwent a complete staging procedure in the early stages and optimal upfront or interval debulking surgery for advanced ovarian cancer. RESULTS: In total, 153 patients were included. Propensity score matching led to the analysis of 41 well-balanced pairs of patients. For a median follow-up of 34.0 [19.0-64.0] months and 38.0 [24.5-75.0] months, respectively, no difference was found between the two groups in regards to overall survival (p=0.28) and disease-free survival (p=0.89). CONCLUSION: In well-selected patients, laparoscopic surgery may be a safe and effective alternative to laparotomy.