H Amarens Geuzinge1, Eveline A M Heijnsdijk2, Inge-Marie Obdeijn3, Harry J de Koning4, Madeleine M A Tilanus-Linthorst5. 1. Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands. Electronic address: h.geuzinge@erasmusmc.nl. 2. Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands. Electronic address: e.heijnsdijk@erasmusmc.nl. 3. Department of Radiology and Nuclear Medicine, Erasmus MC, Erasmus University Medical Centre, Rotterdam, the Netherlands. Electronic address: a.obdeijn@erasmusmc.nl. 4. Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands. Electronic address: h.dekoning@erasmusmc.nl. 5. Department of Surgery, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, the Netherlands. Electronic address: madeleinetilanus@hotmail.com.
Abstract
BACKGROUND: Several studies have investigated MRI breast cancer screening in women at increased risk, but little is known about their preferences. In this study, experiences, expectations and preferences for MRI and mammography were evaluated among women undergoing screening with MRI and/or mammography in the randomized FaMRIsc trial. METHODS: A 17-item questionnaire was sent to 412 women in the FaMRIsc trial. Participants were aged 30-55 years, had a ≥20% cumulative lifetime risk, but no BRCA1/2 or TP53 gene variant, and were screened outside the population-based screening program. Women received annual mammography (mammography-group), or annual MRI and biennial mammography (MRI-group). We asked whether women trust the screening outcome, what they consider as (dis)advantages, which screening they prefer and what they expect of the early detection by the screening tools. RESULTS: 255 (62%) women completed our questionnaire. The high chance of early cancer detection was the most important advantage of MRI screening (MRI-group: 95%; mammography-group: 74%), while this was also the main advantage of mammography (MRI-group: 57%; mammography-group: 72%). Most important disadvantages of MRI were the small tunnel and the contrast fluid (for 23-36%), and of mammography were its painfulness and X-radiation (for 48-60%). Almost the whole MRI-group and half the mammography-group preferred screening with MRI (either alone or with mammography). DISCUSSION: Most women would prefer screening with MRI. The way women think of MRI and mammography is influenced by the screening strategy they are undergoing. Our outcomes can be used for creating information brochures when MRI will be implemented for more women.
RCT Entities:
BACKGROUND: Several studies have investigated MRI breast cancer screening in women at increased risk, but little is known about their preferences. In this study, experiences, expectations and preferences for MRI and mammography were evaluated among women undergoing screening with MRI and/or mammography in the randomized FaMRIsc trial. METHODS: A 17-item questionnaire was sent to 412 women in the FaMRIsc trial. Participants were aged 30-55 years, had a ≥20% cumulative lifetime risk, but no BRCA1/2 or TP53 gene variant, and were screened outside the population-based screening program. Women received annual mammography (mammography-group), or annual MRI and biennial mammography (MRI-group). We asked whether women trust the screening outcome, what they consider as (dis)advantages, which screening they prefer and what they expect of the early detection by the screening tools. RESULTS: 255 (62%) women completed our questionnaire. The high chance of early cancer detection was the most important advantage of MRI screening (MRI-group: 95%; mammography-group: 74%), while this was also the main advantage of mammography (MRI-group: 57%; mammography-group: 72%). Most important disadvantages of MRI were the small tunnel and the contrast fluid (for 23-36%), and of mammography were its painfulness and X-radiation (for 48-60%). Almost the whole MRI-group and half the mammography-group preferred screening with MRI (either alone or with mammography). DISCUSSION: Most women would prefer screening with MRI. The way women think of MRI and mammography is influenced by the screening strategy they are undergoing. Our outcomes can be used for creating information brochures when MRI will be implemented for more women.
Authors: Susana I S Patuleia; Cathy B Moelans; Jasmijn Koopman; Julia E C van Steenhoven; Thijs van Dalen; Carmen C van der Pol; Agnes Jager; Margreet G E M Ausems; Paul J van Diest; Elsken van der Wall; Karijn P M Suijkerbuijk Journal: BMC Cancer Date: 2022-06-27 Impact factor: 4.638