Literature DB >> 3351367

The confirmation of norethindrone aromatization in primary human hepatocytes by the Vitafiber-II cell culture system.

T Yamamoto1, J Kitawaki, K Shiroshita, M Urabe, J Sasaki, M Fukuoka, K Naitoh, H Honjo, H Okada.   

Abstract

A portion of norethindrone (17 alpha-ethynyl-19-nortestosterone) was confirmed to be aromatized to ethynyl estradiol (17 alpha-ethynyl estradiol) in primary human hepatocytes cultured using the Vitafiber-II cell culture system.

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Year:  1988        PMID： 3351367

Source DB:  PubMed          Journal:  Nihon Sanka Fujinka Gakkai Zasshi        ISSN： 0300-9165


  3 in total

1.  Norethisterone Reduces Vaginal Bleeding Caused by Progesterone-Only Birth Control Pills.

Authors:  Naama Vilk Ayalon; Lior Segev; Abraham O Samson; Simcha Yagel; Sarah M Cohen; Tamar Green; Hila Hochler
Journal:  J Clin Med       Date:  2022-06-13       Impact factor: 4.964

2.  Investigations on the in vitro metabolism of five synthetic 19-norprogestins using hepatocyte suspensions isolated from five laboratory animal species.

Authors:  L Qi-Gui; Z Ming-Da; M Hümpel
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1991 Apr-Jun       Impact factor: 2.441

3.  Pharmacokinetics, hydrolysis and aromatisation of norethisterone-3-oxime in female cynomolgus monkey.

Authors:  Q G Li; M Hümpel
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1992 Oct-Dec       Impact factor: 2.441
  3 in total

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