Literature DB >> 33511975

Hepatitis C virus (HCV) diagnosis via microfluidics.

Vigneswaran Narayanamurthy1, Z E Jeroish, K S Bhuvaneshwari, Fahmi Samsuri.   

Abstract

Humans are subjected to various diseases; hence, proper diagnosis helps avoid further disease consequences. One such severe issue that could cause significant damage to the human liver is the hepatitis C virus (HCV). Several techniques are available to detect HCV under various categories, such as detection through antibodies, antigens, and RNA. Although immunoassays play a significant role in discovering hepatitis viruses, there is a need for point-of-care tests (POCT). Some developing strategies are required to ensure the appropriate selection of POCT for HCV detection, initiate appropriate antiviral therapy, and define associated risks, which will be critical in achieving optimal outcomes. Though molecular assays are precise, reproducible, sensitive, and specific, alternative strategies are required to enhance HCV diagnosis among the infected population. Herein, we described and assessed the potential of various microfluidic detection techniques and confirmatory approaches used in present communities. In addition, current key market players in HCV chip-based diagnosis and the future perspectives on the basis of which the diagnosis can be made easier are presented in the present review.

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Mesh:

Year:  2021        PMID: 33511975     DOI: 10.1039/d0ay02045a

Source DB:  PubMed          Journal:  Anal Methods        ISSN: 1759-9660            Impact factor:   2.896


  3 in total

Review 1.  Microheater: material, design, fabrication, temperature control, and applications-a role in COVID-19.

Authors:  Z E Jeroish; K S Bhuvaneshwari; Fahmi Samsuri; Vigneswaran Narayanamurthy
Journal:  Biomed Microdevices       Date:  2021-12-03       Impact factor: 3.783

2.  RT-LAMP-Based Molecular Diagnostic Set-Up for Rapid Hepatitis C Virus Testing.

Authors:  Sandhya Sharma; Emmanuel Thomas; Massimo Caputi; Waseem Asghar
Journal:  Biosensors (Basel)       Date:  2022-05-05

3.  Rapid Visual Detection of Hepatitis C Virus Using Reverse Transcription Recombinase-Aided Amplification-Lateral Flow Dipstick.

Authors:  Haili Wang; Yuhang Zhang; Jingming Zhou; Ming Li; Yumei Chen; Yankai Liu; Hongliang Liu; Peiyang Ding; Chao Liang; Xifang Zhu; Ying Zhang; Cheng Xin; Gaiping Zhang; Aiping Wang
Journal:  Front Cell Infect Microbiol       Date:  2022-02-17       Impact factor: 5.293

  3 in total

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