| Literature DB >> 33511954 |
Eduardo Fuentes1, Andrés Trostchansky2, Lívia Mateus Reguengo3, Mario Roberto Maróstica3, Iván Palomo1.
Abstract
Cardiovascular diseases (CVD) currently account for nearly half of no communicable diseases. Epidemiological studies have demonstrated the cardiovascular protective role of a diet rich in vegetables and fruits. In this context, our research outcomes have demonstrated the antiplatelet activities of fruits and vegetable extracts widely consumed, among which tomato was highlighted in our lab work. Tomato pomace, a major byproduct of tomato paste production, consists of skin and seeds and is a rich source of bioactive compounds. Tomato pomace has potent antithrombotic effects, even greater than the tomato. Given the large volumes of an industrial generation of tomato pomace, there is an opportunity to use this by-product to obtain a functional product with antiaggregant and antithrombotic properties that could be useful as an additive in health foods and thus prevent CVD. This review will focus on the platelet as the target for the antithrombotic actions exerted by the different bioactive compounds present in tomato pomace. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: cardiovascular diseases; platelets; antithrombotic; platelet aggregation; tomato pomace; polyphenols; lycopene.
Year: 2021 PMID: 33511954 DOI: 10.2174/1389450122999210128180456
Source DB: PubMed Journal: Curr Drug Targets ISSN: 1389-4501 Impact factor: 3.465