Literature DB >> 33510099

Corrigendum: A novel tissue engineered nerve graft constructed with autologous vein and nerve microtissue repairs a long-segment sciatic nerve defect.

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Abstract

[This corrects the article DOI: 10.4103/1673-5374.286977.

Entities:  

Year:  2021        PMID: 33510099      PMCID: PMC8328789          DOI: 10.4103/1673-5374.303538

Source DB:  PubMed          Journal:  Neural Regen Res        ISSN: 1673-5374            Impact factor:   5.135


In the article titled “A novel tissue engineered nerve graft constructed with autologous vein and nerve microtissue repairs a long-segment sciatic nerve defect”, published on pages 143–149, Issue 1, Volume 16 of Neural Regeneration Research (Wang et al., 2021), there was an error in the placement of immunofluorescence images in Figure 2A and there was also an error regarding scale bars in Figure 2 legend. The correct Figure 2A and legend are shown as follows:
Figure 2

Preparation and detection of nerve microtissue.

(A) The cells proliferating from the microtissues were stained with S100 and DAPI, which confirmed that they were Schwann cells. The optical microscope images show enlarged views of the area in the black rectangle. With increasing time in culture, the proliferation of cells around the nerve microtissue increased gradually, and the morphology was still long and narrow. Scale bars: 500 µm in the microtissue column, 200 µm in the optical microscope column, 100 µm in the left two immunofluorescence columns, and 50 µm in the right immunofluorescence column. (B) The enzyme-linked immunosorbent assay results showed that nerve microtissues can secrete large amounts of NGF, VEGF and GDNF (n = 3 independently repeated assay for each group). Data are expressed as the mean ± SD. **P < 0.01 (one-way analysis of variance followed by Tukey's post hoc test). DAPI: 4',6-Diamidino2-phenylindole; GDNF: glial cell line-derived neurotrophic factor; NF200: neurofilament 200; NGF: nerve growth factor; n.s.: not significant; VEGF: vascular endothelial growth factor.

Preparation and detection of nerve microtissue. (A) The cells proliferating from the microtissues were stained with S100 and DAPI, which confirmed that they were Schwann cells. The optical microscope images show enlarged views of the area in the black rectangle. With increasing time in culture, the proliferation of cells around the nerve microtissue increased gradually, and the morphology was still long and narrow. Scale bars: 500 µm in the microtissue column, 200 µm in the optical microscope column, 100 µm in the left two immunofluorescence columns, and 50 µm in the right immunofluorescence column. (B) The enzyme-linked immunosorbent assay results showed that nerve microtissues can secrete large amounts of NGF, VEGF and GDNF (n = 3 independently repeated assay for each group). Data are expressed as the mean ± SD. **P < 0.01 (one-way analysis of variance followed by Tukey's post hoc test). DAPI: 4',6-Diamidino2-phenylindole; GDNF: glial cell line-derived neurotrophic factor; NF200: neurofilament 200; NGF: nerve growth factor; n.s.: not significant; VEGF: vascular endothelial growth factor. The online version of the original article can be found under https://doi.org/10.4103/1673-5374.286977.
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1.  A novel tissue engineered nerve graft constructed with autologous vein and nerve microtissue repairs a long-segment sciatic nerve defect.

Authors:  Jing Wang; Ya-Qiong Zhu; Yu Wang; Hong-Guang Xu; Wen-Jing Xu; Yue-Xiang Wang; Xiao-Qing Cheng; Qi Quan; Yong-Qiang Hu; Chang-Feng Lu; Yan-Xu Zhao; Wen Jiang; Chen Liu; Liang Xiao; Wei Lu; Chen Zhu; Ai-Yuan Wang
Journal:  Neural Regen Res       Date:  2021-01       Impact factor: 5.135

  1 in total

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