Literature DB >> 3350799

A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor.

E Knight1, D Fahey, B Cordova, M Hillman, R Kutny, N Reich, D Blomstrom.   

Abstract

An interferon-induced 15-kDa protein is synthesized from a precursor of higher molecular weight; the precursor contains 165 amino acids (17 kDa), whereas the stable product (15 kDa) contains 156 amino acids. The stable 15-kDa form is derived from the precursor 17-kDa form by the removal of eight amino acids from the COOH terminus and the methionine from the NH2 terminus. The existence of the precursor 17-kDa protein can be demonstrated after brief periods of in vivo labeling with [35S]methionine and by translation of mRNA in vitro.

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Year:  1988        PMID: 3350799

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  25 in total

1.  Dysregulation of protein modification by ISG15 results in brain cell injury.

Authors:  Kenneth J Ritchie; Michael P Malakhov; Christopher J Hetherington; Liming Zhou; Marie-Terese Little; Oxana A Malakhova; Jack C Sipe; Stuart H Orkin; Dong-Er Zhang
Journal:  Genes Dev       Date:  2002-09-01       Impact factor: 11.361

2.  Genetic analyses of processing involving C-terminal cleavage in penicillin-binding protein 3 of Escherichia coli.

Authors:  H Hara; Y Nishimura; J Kato; H Suzuki; H Nagasawa; A Suzuki; Y Hirota
Journal:  J Bacteriol       Date:  1989-11       Impact factor: 3.490

Review 3.  Emerging roles for immunomodulatory functions of free ISG15.

Authors:  Jessica A Campbell; Deborah J Lenschow
Journal:  J Interferon Cytokine Res       Date:  2013-09-06       Impact factor: 2.607

4.  The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme.

Authors:  Holger A Lindner; Nasser Fotouhi-Ardakani; Viktoria Lytvyn; Paule Lachance; Traian Sulea; Robert Ménard
Journal:  J Virol       Date:  2005-12       Impact factor: 5.103

Review 5.  Interferon-stimulated gene 15 and the protein ISGylation system.

Authors:  Dongxian Zhang; Dong-Er Zhang
Journal:  J Interferon Cytokine Res       Date:  2010-12-29       Impact factor: 2.607

6.  Zebrafish ISG15 exerts a strong antiviral activity against RNA and DNA viruses and regulates the interferon response.

Authors:  C Langevin; L M van der Aa; A Houel; C Torhy; V Briolat; A Lunazzi; A Harmache; M Bremont; J-P Levraud; P Boudinot
Journal:  J Virol       Date:  2013-07-03       Impact factor: 5.103

7.  Complementary deoxyribonucleic acid sequence encoding bovine ubiquitin cross-reactive protein : A comparison with ubiquitin and a 15-kDa ubiquitin homolog.

Authors:  K J Austin; J K Pru; T R Hansen
Journal:  Endocrine       Date:  1996-10       Impact factor: 3.633

8.  An Ubiquitin-like Motif in ASK1 Mediates its Association with and Inhibition of the Proteasome.

Authors:  Jeffrey R Schneider; James P Lodolce; David L Boone
Journal:  J Biochem Pharmacol Res       Date:  2013-09-01

9.  Cell type-dependent regulation of free ISG15 levels and ISGylation.

Authors:  Angeles C Tecalco Cruz; Karen Mejía-Barreto
Journal:  J Cell Commun Signal       Date:  2017-03-11       Impact factor: 5.782

10.  Immunoregulatory properties of ISG15, an interferon-induced cytokine.

Authors:  J D'Cunha; E Knight; A L Haas; R L Truitt; E C Borden
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-09       Impact factor: 11.205

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