Literature DB >> 33507769

Relapse after incentivized choice treatment in humans: A laboratory model for studying behavior change.

Eric A Thrailkill1, José A Alcalá2.   

Abstract

Behavior change interventions that incentivize desired behavior are highly effective for improving personal health, but difficult to maintain long term. Relapse is common and examining the mechanisms that contribute to relapse in experimental settings can identify processes relevant to substance abuse treatment. We developed a laboratory task that parallels a recent operant model of relapse after incentivized choice reported in the rodent laboratory. In two experiments, undergraduate participants first learned to make an operant response (keyboard button; R1) to earn a reinforcer consisting of an image of a preferred snack food (O1). In a second phase (Phase 2), R1 was still reinforced, but a new response (R2) was introduced and reinforced with a different reinforcer (a coin; O2). In a test phase, contingent incentives for R2 were removed (extinction) and relapse of R1 was assessed. Experiment 1 found that the O2 contingency suppressed R1 during Phase 2, and R1 relapsed rapidly in the test. Neither effect was consistently related to O2 value. Experiment 2 examined whether noncontingent presentations of O1 or O2 during the test could weaken relapse. Here, we found that noncontingent reinforcers did little to reduce or slow the increase in R1 responding. The present experiments highlight a laboratory approach to studying variables that may influence relapse after incentivized treatment. We identify and discuss areas for development to address differences between the present results and prior observations from animal and clinical studies. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

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Year:  2021        PMID: 33507769      PMCID: PMC8363208          DOI: 10.1037/pha0000443

Source DB:  PubMed          Journal:  Exp Clin Psychopharmacol        ISSN: 1064-1297            Impact factor:   3.157


  56 in total

1.  Choice as time allocation.

Authors:  W M Baum; H C Rachlin
Journal:  J Exp Anal Behav       Date:  1969-11       Impact factor: 2.468

2.  Evidence of a goal-directed process in human Pavlovian-instrumental transfer.

Authors:  Tina Seabrooke; Mike E Le Pelley; Lee Hogarth; Chris J Mitchell
Journal:  J Exp Psychol Anim Learn Cogn       Date:  2017-06-19       Impact factor: 2.478

3.  Renewal after the punishment of free operant behavior.

Authors:  Mark E Bouton; Scott T Schepers
Journal:  J Exp Psychol Anim Learn Cogn       Date:  2014-12-01       Impact factor: 2.478

Review 4.  Occasion setting, inhibition, and the contextual control of extinction in Pavlovian and instrumental (operant) learning.

Authors:  Sydney Trask; Eric A Thrailkill; Mark E Bouton
Journal:  Behav Processes       Date:  2016-10-06       Impact factor: 1.777

Review 5.  The use of crowdsourcing in addiction science research: Amazon Mechanical Turk.

Authors:  Justin C Strickland; William W Stoops
Journal:  Exp Clin Psychopharmacol       Date:  2018-11-29       Impact factor: 3.157

Review 6.  Developing human laboratory models of smoking lapse behavior for medication screening.

Authors:  Sherry A McKee
Journal:  Addict Biol       Date:  2008-10-09       Impact factor: 4.280

7.  Contextual renewal of cocaine seeking in rats and its attenuation by the conditioned effects of an alternative reinforcer.

Authors:  David N Kearns; Stanley J Weiss
Journal:  Drug Alcohol Depend       Date:  2007-04-23       Impact factor: 4.492

8.  Context change explains resurgence after the extinction of operant behavior.

Authors:  Sydney Trask; Scott T Schepers; Mark E Bouton
Journal:  Rev Mex Anal Conducta       Date:  2015-09

9.  Relapse of operant behavior after response elimination with an extinction or an omission contingency.

Authors:  Catalina N Rey; Eric A Thrailkill; Kate L Goldberg; Mark E Bouton
Journal:  J Exp Anal Behav       Date:  2019-12-13       Impact factor: 2.468

Review 10.  BEHAVIORAL AND NEUROBIOLOGICAL MECHANISMS OF PAVLOVIAN AND INSTRUMENTAL EXTINCTION LEARNING.

Authors:  Mark E Bouton; Stephen Maren; Gavan P McNally
Journal:  Physiol Rev       Date:  2020-09-24       Impact factor: 37.312

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