[IMAGEN and beyond: novel population neuroscientific strategies for clinical and global cohorts in the STRATIFY and GIGA consortia].

Cohort studies provide the possibility to more precisely define treatment and preventive approaches to mental diseases, when genetic and personal influences as well as sociocultural and environmental factors and their interactions are taken into account. This article presents cohort research approaches, which are dedicated to this aim and reports the lessons learnt and achievements made in the IMAGEN cohort study and the resulting further developments. Specifically, we focus on novel assessment instruments, the implementation of larger clinical and geographic ranges and innovative forms of data analysis.