Literature DB >> 33506311

The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer's disease and dementia with Lewy bodies.

Pinar Soysal1, Semen Gokce Tan2.   

Abstract

This study was aimed to compare early-stage Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), the two most common types of dementia in the elderly, in terms of the prevalence of geriatric syndromes. Patients with early-stage dementia with DLB and AD were included, and were questioned in terms of geriatric syndromes including polypharmacy, malnutrition, frailty, sarcopenia, dynapenia, orthostatic hypotension (OH), urinary and fecal incontinence, falls, fear of falling (FoF), depression, insomnia, excessive daytime sleepiness, pressure ulcers. Of the 82 patients, 31 had DLB and 51 had AD. The mean age was 80.99 ± 7.01, and 69.5% was female. The presence of OH, FoF, depression, and insomnia were more common in the DLB than AD (p < 0.05). 90.3% of patients with DLB and 54.9% of patients with AD had ≥ 3 geriatric syndromes simultaneously. The presence and co-incidence of geriatric syndromes is common in patients with even early-stage DLB and AD.

Entities:  

Keywords:  Alzheimer’s disease; Dementia with Lewy bodies; Geriatric syndromes

Year:  2021        PMID: 33506311     DOI: 10.1007/s40520-020-01774-y

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


  15 in total

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Authors:  Guy M McKhann; David S Knopman; Howard Chertkow; Bradley T Hyman; Clifford R Jack; Claudia H Kawas; William E Klunk; Walter J Koroshetz; Jennifer J Manly; Richard Mayeux; Richard C Mohs; John C Morris; Martin N Rossor; Philip Scheltens; Maria C Carrillo; Bill Thies; Sandra Weintraub; Creighton H Phelps
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2.  Care dependency and nursing care problems in nursing home residents with and without dementia: a cross-sectional study.

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Journal:  Aging Clin Exp Res       Date:  2014-12-20       Impact factor: 3.636

3.  A comparison of the prevalence of orthostatic hypotension between older patients with Alzheimer's Disease, Lewy body dementia, and without dementia.

Authors:  Ahmet Turan Isik; Suleyman Emre Kocyigit; Lee Smith; Ali Ekrem Aydin; Pinar Soysal
Journal:  Exp Gerontol       Date:  2019-06-04       Impact factor: 4.032

4.  The relationship between polypharmacy and trajectories of cognitive decline in people with dementia: A large representative cohort study.

Authors:  Pinar Soysal; Gayan Perera; Ahmet Turan Isik; Graziano Onder; Mirko Petrovic; Antonio Cherubini; Stefania Maggi; Hitesh Shetty; Mariam Molokhia; Lee Smith; Brendon Stubbs; Robert Stewart; Nicola Veronese; Christoph Mueller
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Journal:  Arch Gerontol Geriatr       Date:  2019-12-10       Impact factor: 3.250

6.  Severe Fear of Falling Is Associated With Cognitive Decline in Older Adults: A 3-Year Prospective Study.

Authors:  Hye-Mi Noh; Yong Kyun Roh; Hong Ji Song; Yong Soon Park
Journal:  J Am Med Dir Assoc       Date:  2019-07-24       Impact factor: 4.669

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Journal:  Exp Gerontol       Date:  2018-02-13       Impact factor: 4.032

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Journal:  Neurology       Date:  2017-06-07       Impact factor: 9.910

9.  Frequency and coincidence of geriatric syndromes according to age groups: single-center experience in Turkey between 2013 and 2017.

Authors:  Esra Ates Bulut; Pinar Soysal; Ahmet Turan Isik
Journal:  Clin Interv Aging       Date:  2018-10-04       Impact factor: 4.458

10.  Relationship between comprehensive geriatric assessment and amyloid PET in older persons with MCI.

Authors:  Fulvio Lauretani; Livia Ruffini; Maura Scarlattei; Marcello Maggio
Journal:  BMC Geriatr       Date:  2020-09-09       Impact factor: 3.921

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2.  Outcomes of Care by Geriatricians and Non-geriatricians in an Academic Hospital.

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Journal:  Front Med (Lausanne)       Date:  2022-09-06

5.  The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia.

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  5 in total

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