Literature DB >> 33505815

Treating Mooren's Ulcer - Squeezing Water From a Stone.

Aamir Husain1, Amna Saleem2, Zain Ali Zaidi3, Zohra Kazmi4, Uzzam Ahmed Khawaja3,5.   

Abstract

Mooren's ulcer, a rare ophthalmic disease, presents clinically as a painful, chronic, peripheral corneal ulceration of unknown etiology with some autoimmune origin evidence. It begins with an intense limbal inflammation, leaving behind an opaque cornea. If left untreated, progressive damage and corneal degeneration can lead to permanent loss of vision. Herein, we present a classic case of Mooren's ulcer in the right eye of a 60-year-old male patient with no known comorbid condition. No underlying systemic disorder being the rarity in our case, the cause remains idiopathic. The patient was previously diagnosed with having Mooren's ulcer in his left eye 10 years ago. Despite multiple topical treatments and surgical interventions, there was a complete loss of vision. He presented exaggerated manifestations, including pain, redeye, watery eye, photophobia, and the progressive decline of vision. A combination of multiple pharmacological and surgical interventions, including lateral tarsorrhaphy, amniotic membrane grafting, conjunctival flap, and scleral patch graft, was tried to ameliorate the affected eye but failed to salvage the eye permanently.
Copyright © 2020, Husain et al.

Entities:  

Keywords:  idiopathic; immunosuppression; mooren's ulcer; tarsorrhaphy; topical treatment

Year:  2020        PMID: 33505815      PMCID: PMC7822094          DOI: 10.7759/cureus.12248

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  9 in total

Review 1.  Interventions for Mooren's ulcer.

Authors:  Mahmoud B Alhassan; Mansur Rabiu; Idris O Agbabiaka
Journal:  Cochrane Database Syst Rev       Date:  2014-01-22

Review 2.  Mooren's ulcer: current concepts in management.

Authors:  V S Sangwan; P Zafirakis; C S Foster
Journal:  Indian J Ophthalmol       Date:  1997-03       Impact factor: 1.848

3.  Indications, surgical technique, and results of thin conjunctival flaps on the cornea: a review of 122 consecutive cases.

Authors:  D Paton; A T Milauskas
Journal:  Int Ophthalmol Clin       Date:  1970

Review 4.  Surgical management of corneal ulceration and perforation.

Authors:  S L Portnoy; M S Insler; H E Kaufman
Journal:  Surv Ophthalmol       Date:  1989 Jul-Aug       Impact factor: 6.048

5.  Conjunctival flaps.

Authors:  A M Alino; H D Perry; A J Kanellopoulos; E D Donnenfeld; E K Rahn
Journal:  Ophthalmology       Date:  1998-06       Impact factor: 12.079

Review 6.  Treatment and non-treatment related ocular manifestations in patients with chronic hepatitis B or C.

Authors:  A Tsoumani; V Theopistos; K Katsanos; I Asproudis; E V Tsianos
Journal:  Eur Rev Med Pharmacol Sci       Date:  2013-04       Impact factor: 3.507

7.  Performing a tarsorrhaphy.

Authors:  Saul Rajak; Juliette Rajak; Dinesh Selva
Journal:  Community Eye Health       Date:  2015

8.  Corneoscleral graft in Mooren's ulcer: a case report.

Authors:  Mauro Cellini; Michela Fresina; Ernesto Strobbe; Corrado Gizzi; Emilio C Campos
Journal:  Cases J       Date:  2009-11-02

9.  Case report: bilateral Mooren ulcer in association with hepatitis C.

Authors:  Vesa Aaltonen; Mari Alavesa; Laura Pirilä; Eija Vesti; Mohammad Al-Juhaish
Journal:  BMC Ophthalmol       Date:  2017-12-06       Impact factor: 2.209

  9 in total

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