Ana Maria Cunha1, Marta Silva1, Ana Catarina Pedrosa1, Fernando Falcão-Reis1,2, Luís Figueira1,3,4. 1. Department of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal. 2. Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal. 3. Department of Pharmacology and Therapeutics, Faculty of Medicine of the University of Porto, Porto, Portugal. 4. Center for Drug Discovery and Innovative Medicines (MedInUP), University of Porto, Porto, Portugal.
Abstract
PURPOSE: To describe a positive clinical response of a patient with submacular Nocardia abscess due to a rapid and efficient treatment. Case report. We describe a case of a 50-year-old man with a painless visual decline of the left eye. Four years later, he had been diagnosed with systemic nocardiosis. Examination of the left eye revealed a submacular white mass with fluffy borders and another smaller white lesion, with well-defined borders, in the inferior temporal vascular arch. A systemic antibiotic treatment with SMX-TMP and intravenous imipenem and a single intravitreal injection of bevacizumab was performed. CONCLUSION: Prompt diagnosis and treatment ensured an expeditious resolution of the abscess and significant improvement of visual acuity. The diagnostic approach of a high index of suspicion coupled with directed treatment is required when dealing with subretinal inflammatory lesions.
PURPOSE: To describe a positive clinical response of a patient with submacular Nocardia abscess due to a rapid and efficient treatment. Case report. We describe a case of a 50-year-old man with a painless visual decline of the left eye. Four years later, he had been diagnosed with systemic nocardiosis. Examination of the left eye revealed a submacular white mass with fluffy borders and another smaller white lesion, with well-defined borders, in the inferior temporal vascular arch. A systemic antibiotic treatment with SMX-TMP and intravenous imipenem and a single intravitreal injection of bevacizumab was performed. CONCLUSION: Prompt diagnosis and treatment ensured an expeditious resolution of the abscess and significant improvement of visual acuity. The diagnostic approach of a high index of suspicion coupled with directed treatment is required when dealing with subretinal inflammatory lesions.
Authors: P D Weishaar; H W Flynn; T G Murray; J L Davis; C C Barr; J G Gross; C E Mein; W C McLean; J H Killian Journal: Ophthalmology Date: 1998-01 Impact factor: 12.079