Literature DB >> 33505528

Assessment of genetically modified maize MON 87427 × MON 87460 × MON 89034 × 1507 × MON 87411 × 59122 and subcombinations, for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2017-139).

Hanspeter Naegeli, Jean-Louis Bresson, Tamas Dalmay, Ian Crawford Dewhurst, Michelle M Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejatko, Francisco Javier Moreno, Ewen Mullins, Fabien Nogué, Nils Rostoks, Jose Juan Sánchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Fernando Álvarez, Michele Ardizzone, Giacomo De Sanctis, Antonio Fernandez, Andrea Gennaro, Jose Ángel Gómez Ruiz, Dafni Maria Kagkli, Anna Lanzoni, Franco Maria Neri, Nikoletta Papadopoulou, Konstantinos Paraskevopoulos, Tommaso Raffaello.   

Abstract

Maize MON 87427 × MON 87460 × MON 89034 × 1507 × MON 87411 × 59122 (six-event stack maize) was produced by conventional crossing to combine six single events: MON 87427, MON 87460, MON 89034, 1507, MON 87411 and 59122. The GMO Panel previously assessed the six single maize events and 17 of the subcombinations and did not identify safety concerns. No new data on the single maize events or the 17 subcombinations were identified that could lead to modification of the original conclusions on their safety. The molecular characterisation, comparative analysis (agronomic, phenotypic and compositional characteristics) and the outcome of the toxicological, allergenicity and nutritional assessment indicate that the combination of the single maize events and of the newly expressed proteins and dsRNA in the six-event stack maize does not give rise to food and feed safety and nutritional concerns. The GMO Panel concludes that the six-event stack maize, as described in this application, is as safe as its non-GM comparator and the selected non-GM reference varieties. In the case of accidental release of viable grains of the six-event stack maize into the environment, this would not raise environmental safety concerns. The GMO Panel assessed the likelihood of interactions among the single events in the 39 maize subcombinations not previously assessed and concludes that these are expected to be as safe as the single events, the previously assessed subcombinations and the six-event stack maize. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of the six-event stack maize. Post-market monitoring of food/feed is not considered necessary. The GMO Panel concludes that the six-event stack maize and its subcombinations are as safe as the non-GM comparator and the selected non-GM reference varieties with respect to potential effects on human and animal health and the environment.
© 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Entities:  

Keywords:  GMO; Zea mays; dsRNA; herbicide tolerant; insect resistant; stack events

Year:  2021        PMID: 33505528      PMCID: PMC7814765          DOI: 10.2903/j.efsa.2021.6351

Source DB:  PubMed          Journal:  EFSA J        ISSN: 1831-4732


  38 in total

1.  The Shikimate Pathway: Early Steps in the Biosynthesis of Aromatic Compounds.

Authors:  K. M. Herrmann
Journal:  Plant Cell       Date:  1995-07       Impact factor: 11.277

2.  Effects of Different Processing Methods on the Micronutrient and Phytochemical Contents of Maize: From A to Z.

Authors:  Devika J Suri; Sherry A Tanumihardjo
Journal:  Compr Rev Food Sci Food Saf       Date:  2016-06-28       Impact factor: 12.811

3.  Expression of bacterial genes in plant cells.

Authors:  R T Fraley; S G Rogers; R B Horsch; P R Sanders; J S Flick; S P Adams; M L Bittner; L A Brand; C L Fink; J S Fry; G R Galluppi; S B Goldberg; N L Hoffmann; S C Woo
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

Review 4.  Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains.

Authors:  Raj Kishor Gupta; Shivraj Singh Gangoliya; Nand Kumar Singh
Journal:  J Food Sci Technol       Date:  2013-04-24       Impact factor: 2.701

5.  Characterization of the herbicide-resistance gene bar from Streptomyces hygroscopicus.

Authors:  C J Thompson; N R Movva; R Tizard; R Crameri; J E Davies; M Lauwereys; J Botterman
Journal:  EMBO J       Date:  1987-09       Impact factor: 11.598

6.  Teosinte in Europe - Searching for the Origin of a Novel Weed.

Authors:  Miluse Trtikova; Andre Lohn; Rosa Binimelis; Ignacio Chapela; Bernadette Oehen; Niklaus Zemp; Alex Widmer; Angelika Hilbeck
Journal:  Sci Rep       Date:  2017-05-08       Impact factor: 4.379

7.  Spread of volunteer and feral maize plants in Central Europe: recent data from Austria.

Authors:  Kathrin Pascher
Journal:  Environ Sci Eur       Date:  2016-12-30       Impact factor: 5.893

8.  Assessment of genetically modified maize MON 89034 × 1507 × NK603 × DAS-40278-9 and subcombinations independently of their origin for food and feed uses, import and processing, under Regulation (EC) No 1829-2003 (application EFSA-GMO-NL-2013-112).

Authors:  Hanspeter Naegeli; Jean-Louis Bresson; Tamas Dalmay; Ian Crawford Dewhurst; Michelle M Epstein; Leslie George Firbank; Philippe Guerche; Jan Hejatko; Francisco Javier Moreno; Ewen Mullins; Fabien Nogué; Nils Rostoks; Jose Juan Sánchez Serrano; Giovanni Savoini; Eve Veromann; Fabio Veronesi; Fernando Álvarez; Michele Ardizzone; Antonio Fernandez Dumont; Andrea Gennaro; Jose Ángel Gómez Ruiz; Anna Lanzoni; Franco Maria Neri; Nikoletta Papadopoulou; Matthew Ramon
Journal:  EFSA J       Date:  2019-01-16

Review 9.  Toxicological evaluation of proteins introduced into food crops.

Authors:  Bruce Hammond; John Kough; Corinne Herouet-Guicheney; Joseph M Jez
Journal:  Crit Rev Toxicol       Date:  2013-11       Impact factor: 5.635

Review 10.  Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition.

Authors:  Guoyao Wu
Journal:  J Anim Sci Biotechnol       Date:  2014-06-14
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  3 in total

Review 1.  Genetic Approaches to Enhance Multiple Stress Tolerance in Maize.

Authors:  Nenad Malenica; Jasenka Antunović Dunić; Lovro Vukadinović; Vera Cesar; Domagoj Šimić
Journal:  Genes (Basel)       Date:  2021-11-04       Impact factor: 4.096

2.  Assessment of genetically modified maize DP4114 × MON 810 × MIR604 × NK603 and subcombinations, for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2018-150).

Authors:  Ewen Mullins; Jean-Louis Bresson; Tamas Dalmay; Ian Crawford Dewhurst; Michelle M Epstein; Leslie George Firbank; Philippe Guerche; Jan Hejatko; Hanspeter Naegeli; Francisco Javier Moreno; Fabien Nogué; Nils Rostoks; Jose Juan Sánchez Serrano; Giovanni Savoini; Eve Veromann; Fabio Veronesi; Michele Ardizzone; Antonio Fernandez Dumont; Silvia Federici; Andrea Gennaro; Jose Ángel Gómez Ruiz; Tilemachos Goumperis; Dafni Maria Kagkli; Anna Lanzoni; Paolo Lenzi; Franco Maria Neri; Nikoletta Papadopoulou; Konstantinos Paraskevopoulos; Tommaso Raffaello; Franz Streissl; Giacomo De Sanctis
Journal:  EFSA J       Date:  2022-03-07

3.  Assessment of genetically modified maize MON 89034 × 1507 × MIR162 × NK603 × DAS-40278-9 for food and feed uses, under regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2018-151).

Authors:  Ewen Mullins; Jean-Louis Bresson; Tamas Dalmay; Ian Crawford Dewhurst; Michelle M Epstein; Leslie George Firbank; Philippe Guerche; Jan Hejatko; Hanspeter Naegeli; Francisco Javier Moreno; Fabien Nogué; Nils Rostoks; Jose Juan Sánchez Serrano; Giovanni Savoini; Eve Veromann; Fabio Veronesi; Michele Ardizzone; Giacomo De Sanctis; Antonio Fernandez Dumont; Silvia Federici; Andrea Gennaro; Jose Angel Gomez Ruiz; Tilemachos Goumperis; Dafni Maria Kagkli; Anna Lanzoni; Paolo Lenzi; Aleksandra Lewandowska; Franco Maria Neri; Konstantinos Paraskevopoulos; Tommaso Raffaello; Franz Streissl
Journal:  EFSA J       Date:  2022-08-12
  3 in total

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