Morten Klitskov Jensen1,2,3, Dan Dupont Hougaard4,5. 1. Department of Otolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital, Aalborg, Denmark. m.klitskov@rn.dk. 2. Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. m.klitskov@rn.dk. 3. Audiological Department, Balance and Dizziness Centre, Havrevangen 1, 9000, Aalborg, Denmark. m.klitskov@rn.dk. 4. Department of Otolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital, Aalborg, Denmark. 5. Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Abstract
PURPOSE: Suppression head impulse testing (SHIMP) is a new vestibular method capable of quantifying vestibular function. The aim of this study was to evaluate the feasibility of this test in patients with existing or newly diagnosed vestibular schwannoma (VS) patients by comparing the results with the traditionally used video head impulse test (vHIT or HIMP). METHODS: Fifty-five patients with unilateral VS underwent a wide battery of audiological and vestibular tests. HIMP results were evaluated using newly introduced objective guidelines based on the trace evaluation of pathological saccades. The sensitivity and specificity of HIMP and SHIMP were evaluated and compared. A new SHIMP parameter is presented; the anticompensatory saccade amplitude ratio (ASAR). RESULTS: We found a marked increase in specificity in HIMP testing using the objective guidelines. SHIMP testing revealed a gain threshold of 0.7 to be optimal in terms of achieving high specificity and sensitivity in relation to HIMP testing. Significant correlations were found between a low ASAR and a high degree of vestibular pathology. CONCLUSION: The SHIMP test is a viable addition to the standard HIMP test in patients with VS, especially with the addition of the ASAR, which could prove useful in monitoring the residual vestibular function. TRIAL REGISTRATION NUMBER AND DATE OF REGISTRATION: N/A.
PURPOSE: Suppression head impulse testing (SHIMP) is a new vestibular method capable of quantifying vestibular function. The aim of this study was to evaluate the feasibility of this test in patients with existing or newly diagnosed vestibular schwannoma (VS) patients by comparing the results with the traditionally used video head impulse test (vHIT or HIMP). METHODS: Fifty-five patients with unilateral VS underwent a wide battery of audiological and vestibular tests. HIMP results were evaluated using newly introduced objective guidelines based on the trace evaluation of pathological saccades. The sensitivity and specificity of HIMP and SHIMP were evaluated and compared. A new SHIMP parameter is presented; the anticompensatory saccade amplitude ratio (ASAR). RESULTS: We found a marked increase in specificity in HIMP testing using the objective guidelines. SHIMP testing revealed a gain threshold of 0.7 to be optimal in terms of achieving high specificity and sensitivity in relation to HIMP testing. Significant correlations were found between a low ASAR and a high degree of vestibular pathology. CONCLUSION: The SHIMP test is a viable addition to the standard HIMP test in patients with VS, especially with the addition of the ASAR, which could prove useful in monitoring the residual vestibular function. TRIAL REGISTRATION NUMBER AND DATE OF REGISTRATION: N/A.
Authors: Tessa van Dooren; Dmitrii Starkov; Florence Lucieer; Bieke Dobbels; Miranda Janssen; Nils Guinand; Angelica Pérez Fornos; Herman Kingma; Vincent Van Rompaey; Raymond van de Berg Journal: J Clin Med Date: 2022-04-26 Impact factor: 4.241