Literature DB >> 3350134

Inhibition by tetanus and botulinum A toxin of the release of [3H]noradrenaline and [3H]GABA from rat brain homogenate.

E Habermann1.   

Abstract

Rat brain homogenate was preloaded with [3H]noradrenaline or [3H]GABA and stimulated with high K+. Tetanus toxin and botulinum A neurotoxin partially prevent the evoked [3H]noradrenaline release in the same range of toxin concentrations starting below 10(-10) M. In contrast, release of gamma-amino butyric acid (GABA) is much more sensitive to tetanus than to botulinum A toxin.

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Year:  1988        PMID： 3350134     DOI： 10.1007/bf01941714

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  Preferential metabolism of (-) 3 H-norepinephrine through the deaminated glycol in the rat vas deferens.

Authors:  K H Graffe; F J Stefano; S Z Langer
Journal:  Biochem Pharmacol       Date:  1973-05-15       Impact factor: 5.858

Review 2.  Clostridial neurotoxins: handling and action at the cellular and molecular level.

Authors:  E Habermann; F Dreyer
Journal:  Curr Top Microbiol Immunol       Date:  1986       Impact factor: 4.291

3.  Tetanus toxin and botulinum A toxin inhibit release and uptake of various transmitters, as studied with particulate preparations from rat brain and spinal cord.

Authors:  H Bigalke; I Heller; B Bizzini; E Habermann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-06       Impact factor: 3.000

4.  Tetanus toxin does not affect the release of noradrenaline and taurine from rat cerebral cortex slices evoked by high K+ and Na+-free media.

Authors:  J Heredero; S S Oja
Journal:  Experientia       Date:  1987-02-15

5.  Tetanus toxin and botulinum A neurotoxin inhibit and at higher concentrations enhance noradrenaline outflow from particulate brain cortex in batch.

Authors:  E Habermann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-12       Impact factor: 3.000
  5 in total
  10 in total

1.  Tetanus toxin: biochemical and pharmacological comparison between its protoxin and some isotoxins obtained by limited proteolysis.

Authors:  U Weller; F Mauler; E Habermann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-08       Impact factor: 3.000

2.  Expression of tetanus toxin subfragments in vitro and characterization of epitopes.

Authors:  B Andersen-Beckh; T Binz; H Kurazono; T Mayer; U Eisel; H Niemann
Journal:  Infect Immun       Date:  1989-11       Impact factor: 3.441

Review 3.  Current Prophylactic Medications for Migraine and Their Potential Mechanisms of Action.

Authors:  Till Sprenger; M Viana; C Tassorelli
Journal:  Neurotherapeutics       Date:  2018-04       Impact factor: 7.620

4.  Role of omega-conotoxin-sensitive calcium channels in inositolphosphate production and noradrenaline release due to potassium depolarization or stimulation with carbachol.

Authors:  F Hofmann; E Habermann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-03       Impact factor: 3.000

5.  Pharmacological and biochemical studies of cytotoxicity of Clostridium novyi type A alpha-toxin.

Authors:  P Bette; J Frevert; F Mauler; N Suttorp; E Habermann
Journal:  Infect Immun       Date:  1989-08       Impact factor: 3.441

Review 6.  Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells.

Authors:  Michel R Popoff; Bernard Poulain
Journal:  Toxins (Basel)       Date:  2010-04-15       Impact factor: 4.546

Review 7.  Current status and future directions of botulinum neurotoxins for targeting pain processing.

Authors:  Sabine Pellett; Tony L Yaksh; Roshni Ramachandran
Journal:  Toxins (Basel)       Date:  2015-11-04       Impact factor: 4.546

8.  Botulinum toxin suppression of CNS network activity in vitro.

Authors:  Joseph J Pancrazio; Kamakshi Gopal; Edward W Keefer; Guenter W Gross
Journal:  J Toxicol       Date:  2014-02-12

9.  Impact of Botox-A SNAP-25 protein expression and the mechanism of inhibitory neurotransmitter imbalance in chronic sciatic nerve pain rat model.

Authors:  Xu-Dong Ding; Wei Wang; Zhi-Gang Ding; Yan-Ping Liu; Jing Zhong; Hua-Xian Chen
Journal:  Exp Ther Med       Date:  2017-04-18       Impact factor: 2.447

Review 10.  New Insights on Metabolic and Genetic Basis of Migraine: Novel Impact on Management and Therapeutical Approach.

Authors:  Irene Simonetta; Renata Riolo; Federica Todaro; Antonino Tuttolomondo
Journal:  Int J Mol Sci       Date:  2022-03-11       Impact factor: 5.923
  10 in total

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