Aamod Dhoj Shrestha1,2, Dinesh Neupane3,4, Sarita Ghimire5, Christine Campbell6, Per Kallestrup7. 1. Center for Global Health, Department of Public Health, Aarhus University, Aarhus, Denmark. aamod.shrestha@gmail.com. 2. COBIN, Nepal Development Society, Bharatpur, Nepal. aamod.shrestha@gmail.com. 3. COBIN, Nepal Development Society, Bharatpur, Nepal. 4. Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. 5. Nepal Cancer Care Foundation, Lalitpur, Nepal. 6. Usher Institute, University of Edinburgh, Edinburgh, EH8 9AG, UK. 7. Center for Global Health, Department of Public Health, Aarhus University, Aarhus, Denmark.
Abstract
BACKGROUND: Previous studies suggest that health intervention designed to increase cervical cancer screening has been effective to reduce cervical cancer incidence and mortality. The aim of this study is to determine the effect of a home-based health education intervention for increasing cervical cancer screening uptake delivered by trained female community health volunteers (FCHVs), a category of community health worker in Nepal. METHODS: A community-based, open-label, two-armed, cluster-randomized trial [seven clusters (geographical wards) randomized for the intervention, and seven for the control arm]. The participants are recruited from a population-based survey with a sample size of 884. Based on population proportion size, 277 women will be recruited for the intervention group and 413 women recruited for the control group. A 12-month community-based health education intervention will be administered mobilizing the FCHVs, based on the Health Belief Model. The primary outcome measure of the study will be the difference in percentage of cervical cancer screening uptake between the two study arms. The primary outcomes will be modeled by using mixed-effect logistic regression analysis. DISCUSSION: COBIN-C is the first study investigating the effect of a community-based health education intervention by FCHVs on increasing cervical cancer screening uptake among women in Nepal. The purpose of this study is to develop and implement a home-based, culturally sensitive program to increase cervical cancer screening coverage at the community level. TRIAL REGISTRATION: ClinicalTrials.gov NCT03808064 . Registered on January 14, 2019.
RCT Entities:
BACKGROUND: Previous studies suggest that health intervention designed to increase cervical cancer screening has been effective to reduce cervical cancer incidence and mortality. The aim of this study is to determine the effect of a home-based health education intervention for increasing cervical cancer screening uptake delivered by trained female community health volunteers (FCHVs), a category of community health worker in Nepal. METHODS: A community-based, open-label, two-armed, cluster-randomized trial [seven clusters (geographical wards) randomized for the intervention, and seven for the control arm]. The participants are recruited from a population-based survey with a sample size of 884. Based on population proportion size, 277 women will be recruited for the intervention group and 413 women recruited for the control group. A 12-month community-based health education intervention will be administered mobilizing the FCHVs, based on the Health Belief Model. The primary outcome measure of the study will be the difference in percentage of cervical cancer screening uptake between the two study arms. The primary outcomes will be modeled by using mixed-effect logistic regression analysis. DISCUSSION: COBIN-C is the first study investigating the effect of a community-based health education intervention by FCHVs on increasing cervical cancer screening uptake among women in Nepal. The purpose of this study is to develop and implement a home-based, culturally sensitive program to increase cervical cancer screening coverage at the community level. TRIAL REGISTRATION: ClinicalTrials.gov NCT03808064 . Registered on January 14, 2019.
Entities:
Keywords:
Cervical cancer screening; Community health worker; Community-based; Female community health volunteers; Nepal; Non-communicable diseases; Randomized controlled trial
Authors: Dinesh Neupane; Craig S McLachlan; Bo Christensen; Arjun Karki; Henry B Perry; Per Kallestrup Journal: Trials Date: 2016-06-18 Impact factor: 2.279