Literature DB >> 33499839

Examining potential effects of non-occupational post-exposure prophylaxis (nPEP) on sexual behaviors of Chinese men who have sex with men: a cross-sectional study.

Haochu Li1, Ran Wei2, Jason J Ong3, Eunsook Kim4, Traci L Weinstein5, Xiaofu Ning6, Wei Ma7.   

Abstract

BACKGROUND: In China, non-occupational post-exposure prophylaxis (nPEP) is not a conventional service yet and nPEP related studies are very few. Recently, China's 13th Five Year Action Plan for HIV/AIDS Containment and Prevention examines the feasibility of including nPEP as one of the national strategies for HIV prevention. However, there is a concern that nPEP use might exacerbate high-risk sexual activities. In order to facilitate a research-based policy making of routinizing nPEP services, the current study examined potential effects of nPEP use on condom use and number of sexual partners among Chinese men who have sex with men (MSM) .
METHODS: A cross-sectional survey was conducted in two cities of China in November and December 2018. Descriptive analyses of participants' sociodemographic and behavioral characteristics were conducted using SPSS 24.0. Mplus 7.4 was used to conduct confirmatory factor analysis and structural equation modeling.
RESULTS: The sample included 419 Chinese MSM with a mean age of 28.04 (SD = 9.71). Participants reported more positive anticipation of their own behaviors than other MSM's behaviors regarding condom use and number of sexual partners if nPEP were to be routinized in China. About 60% of participants reported discrepancies between anticipated individual and population behaviors as a potential result of routinization of nPEP services. Anticipated individual behavioral change was positively related to age and duration of residence in the current city, and negatively related to education. Anticipated population behavioral change was positively related to age. Anticipated behavioral discrepancy was positively related to being ethnic minority and never married.
CONCLUSIONS: These findings identify a high-risk subgroup of MSM, who reported they would use condoms less and/or have more sexual partners when nPEP becomes available. This subgroup of MSM might benefit from targeted health interventions. Moreover, there is a clear discrepancy between anticipated individual and population behavioral changes regarding future routinization of nPEP services, suggesting incorporating nPEP services as a means of community development for MSM.

Entities:  

Keywords:  Anticipated behavioral change; China; Condom use, number of sex partners; Men who have sex with men; Non-occupational post-exposure prophylaxis (nPEP)

Mesh:

Year:  2021        PMID: 33499839      PMCID: PMC7839183          DOI: 10.1186/s12889-021-10283-0

Source DB:  PubMed          Journal:  BMC Public Health        ISSN: 1471-2458            Impact factor:   3.295


  26 in total

1.  High HIV incidence among MSM prescribed postexposure prophylaxis, 2000-2009: indications for ongoing sexual risk behaviour.

Authors:  José Heuker; Gerard J B Sonder; Ineke Stolte; Ronald Geskus; Anneke van den Hoek
Journal:  AIDS       Date:  2012-02-20       Impact factor: 4.177

2.  HIV-Related Training and Correlates of Knowledge, HIV Screening and Prescribing of nPEP and PrEP Among Primary Care Providers in Southeast United States, 2017.

Authors:  Kirk D Henny; Christopher C Duke; Angelica Geter; Zaneta Gaul; Chantell Frazier; Jennifer Peterson; Kate Buchacz; Madeline Y Sutton
Journal:  AIDS Behav       Date:  2019-11

3.  Incidence of sexually transmitted diseases and HIV infection related to perceived HIV/AIDS threat since highly active antiretroviral therapy availability in men who have sex with men.

Authors:  Eric M van der Snoek; John B F de Wit; Paul G H Mulder; Willem I van der Meijden
Journal:  Sex Transm Dis       Date:  2005-03       Impact factor: 2.830

4.  HIV non-occupational postexposure prophylaxis (nPEP) usage among five key populations in China.

Authors:  Haochu Li; Ran Wei; Eduardo Piqueiras; Eric P F Chow; Kedi Jiao; Taylor Lewis; Wei Ma
Journal:  Sex Transm Infect       Date:  2021-01-04       Impact factor: 3.519

5.  Use of postexposure prophylaxis against HIV infection following sexual exposure does not lead to increases in high-risk behavior.

Authors:  Jeffrey N Martin; Michelle E Roland; Torsten B Neilands; Melissa R Krone; Joshua D Bamberger; Robert P Kohn; Margaret A Chesney; Karena Franses; James O Kahn; Thomas J Coates; Mitchell H Katz
Journal:  AIDS       Date:  2004-03-26       Impact factor: 4.177

6.  Cost-effectiveness of HIV nonoccupational post-exposure prophylaxis in Australia.

Authors:  D Guinot; M T Ho; I M Poynten; J McAllister; A Pierce; C Pell; A E Grulich
Journal:  HIV Med       Date:  2009-01-22       Impact factor: 3.180

7.  Prevalence of bisexual behaviors among men who have sex with men (MSM) in China and associations between condom use in MSM and heterosexual behaviors.

Authors:  Joseph T F Lau; Ming Wang; Hong Nei Wong; Hi Yi Tsui; Manhong Jia; Feng Cheng; Yun Zhang; Xiaoyou Su; Ning Wang
Journal:  Sex Transm Dis       Date:  2008-04       Impact factor: 2.830

8.  Behavioral impact, acceptability, and HIV incidence among homosexual men with access to postexposure chemoprophylaxis for HIV.

Authors:  Mauro Schechter; Regina F do Lago; Aaron B Mendelsohn; Ronaldo I Moreira; Lawrence H Moulton; Lee H Harrison
Journal:  J Acquir Immune Defic Syndr       Date:  2004-04-15       Impact factor: 3.731

9.  Nonoccupational postexposure prophylaxis, subsequent risk behaviour and HIV incidence in a cohort of Australian homosexual men.

Authors:  I Mary Poynten; Fengyi Jin; Limin Mao; Garrett P Prestage; Susan C Kippax; John M Kaldor; John Imrie; Andrew E Grulich
Journal:  AIDS       Date:  2009-06-01       Impact factor: 4.177

10.  HIV risk behaviors and testing history in historically black college and university settings.

Authors:  Peter E Thomas; Andrew C Voetsch; Binwei Song; Denyce Calloway; Carolyn Goode; Lynette Mundey; Joanne Nobles; Kaye Sly; Michelle R Smith; Brenda Williams; Mattie Shiloh; Kevin Patterson; Sybil Ward; Patrick S Sullivan; James D Heffelfinger
Journal:  Public Health Rep       Date:  2008 Nov-Dec       Impact factor: 2.792

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