Literature DB >> 33498928

Therapeutic Application of Exosomes in Inflammatory Diseases.

Ju Hun Suh1, Hyeon Su Joo1, Eun Be Hong1, Hyeon Ji Lee1, Jung Min Lee1.   

Abstract

Immunomodulation is on the cusp of being an important therapy for treating many diseases, due to the significant role of the immune system in defending the human body. Although the immune system is an essential defense system, overactivity can result in diverse sicknesses such as inflammation and autoimmune disease. Exosomes are emerging as a state-of-the-art therapeutic strategy for treating an overactive immune system. Thus, exosomes have drawn great interest for their potential clinical applications in treating diseases associated with abnormal immune regulation. Hence, in this review, we will discuss trends in exosome research related to inflammatory and autoimmune diseases. Possible therapeutic applications of exosomes will be summarized. Finally, an outlook to the future of exosomal therapy will be introduced.

Entities:  

Keywords:  autoimmune disease; exosome; immunomodulation; inflammation

Mesh：

Year:  2021        PMID： 33498928      PMCID： PMC7865921          DOI： 10.3390/ijms22031144

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  180 in total

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Review 8.  Designer Exosomes: A New Platform for Biotechnology Therapeutics.

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  7 in total

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2.  A Serum Biomarker Panel of exomiR-451a, exomiR-25-3p and Soluble TWEAK for Early Diagnosis of Rheumatoid Arthritis.

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  7 in total

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