Literature DB >> 334971

Late acting T cell depression of high avidity IgG antibody secretion in the secondary response.

R W Warren, J M Davie.   

Abstract

Activated T lymphocytes (ATC) suppressed the expression of high avidity plaque-forming cells (PFC) in the secondary immune response when given in vivo 1 day before assay or when mixed in vitro with hyperimmune cells for 90 min before assay. This late acting suppression is a cell dose-dependent, carrier-spedific, T cell-mediated phenomenon. The target of this activity if probably the antibody-secreting cell.

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Year:  1977        PMID： 334971

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  2 in total

1.  Adoptive transfer of allotype-specific suppressor cells inhibits thymus-independent immunoglobulin production in syngeneic athymic mice.

Authors:  E B Jacobson
Journal:  J Exp Med       Date:  1978-08-01       Impact factor: 14.307

2.  Immunoregulation of murine myeloma in vitro. II. Suppression of MOPC-315 immunoglobulin secretion and synthesis by idiotype-specific suppressor T cells.

Authors:  G L Milburn; R G Lynch
Journal:  J Exp Med       Date:  1982-03-01       Impact factor: 14.307
  2 in total

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