Literature DB >> 3349590

Symptom scores as measures of the severity of rhinitis.

A Linder1.   

Abstract

Methodological aspects of subjective symptom ratings were investigated in 103 symptomatic rhinitis patients. The patient's own overall rating registered on a visual analogue scale was compared with a summed symptom score calculated from ratings of sneezing, rhinorrhea and congestion. A significant correlation, but not complete correspondence, was found in patients with untreated rhinitis during the birch pollen season and after challenges with birch pollen or histamine. Comparisons between the overall rating and scores for individual symptoms gave lower degrees of correlation or non-significant correlations. When twenty-five patients were treated with an intranasal corticosteroid during the pollen season, both the overall rating and the summed symptom score decreased significantly. The changes in the two ratings for each patient showed a moderate correlation. The patients' ratings of rhinorrhea correlated with an approximate measure of the volume of secretion after pollen challenge but not during the pollen season or after histamine challenge. It is recommended on the basis of these findings that, for measuring the severity of rhinitis, scores indicating the course of individual symptoms should not be combined into a summed score, but that the patient's overall rating of the condition should be used. Scores for individual symptoms can be used to draw more detailed conclusions about nasal pathophysiological features and about qualitative disimilarities between different modes of therapy.

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Year:  1988        PMID: 3349590     DOI: 10.1111/j.1365-2222.1988.tb02840.x

Source DB:  PubMed          Journal:  Clin Allergy        ISSN: 0009-9090


  21 in total

Review 1.  Human nasal allergen provocation for determination of true allergic rhinitis: methods for clinicians.

Authors:  Ludmila I Litvyakova; James N Baraniuk
Journal:  Curr Allergy Asthma Rep       Date:  2002-05       Impact factor: 4.806

2.  [The NTP in allergy research : open questions regarding nasal provocation tests using allergens].

Authors:  U Förster; A Sperl; L Klimek
Journal:  HNO       Date:  2013-10       Impact factor: 1.284

3.  Acoustic evaluation of the efficacy of medical therapy for allergic nasal obstruction.

Authors:  M Yamagiwa
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 2.503

Review 4.  Treatment of hay fever.

Authors:  S F Wood
Journal:  J R Coll Gen Pract       Date:  1989-07

5.  A placebo controlled study comparing the efficacy of intranasal azelastine and beclomethasone in the treatment of seasonal allergic rhinitis.

Authors:  G Newson-Smith; M Powell; M Baehre; S P Garnham; M T MacMahon
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 2.503

6.  A multicenter clinical study of the efficacy and tolerability of azelastine nasal spray in the treatment of seasonal allergic rhinitis: a comparison with oral cetirizine.

Authors:  D Charpin; P Godard; R P Garay; M Baehre; D Herman; F B Michel
Journal:  Eur Arch Otorhinolaryngol       Date:  1995       Impact factor: 2.503

7.  Randomised controlled trial of homoeopathy versus placebo in perennial allergic rhinitis with overview of four trial series.

Authors:  M A Taylor; D Reilly; R H Llewellyn-Jones; C McSharry; T C Aitchison
Journal:  BMJ       Date:  2000 Aug 19-26

8.  Effects of omalizumab on basophil and mast cell responses using an intranasal cat allergen challenge.

Authors:  John A Eckman; Patricia M Sterba; Denise Kelly; Val Alexander; Mark C Liu; Bruce S Bochner; Donald W Macglashan; Sarbjit S Saini
Journal:  J Allergy Clin Immunol       Date:  2009-12-04       Impact factor: 10.793

9.  Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system.

Authors:  Meixia Gao; Anju Singh; Kristin Macri; Curt Reynolds; Vandana Singhal; Shyam Biswal; Ernst W Spannhake
Journal:  Respir Res       Date:  2011-07-13

Review 10.  Clinical Research Needs for the Management of Chronic Rhinosinusitis with Nasal Polyps in the New Era of Biologics: A National Institute of Allergy and Infectious Diseases Workshop.

Authors:  Robert Naclerio; Fuad Baroody; Claus Bachert; Benjamin Bleier; Larry Borish; Erica Brittain; Geoffrey Chupp; Anat Fisher; Wytske Fokkens; Philippe Gevaert; David Kennedy; Jean Kim; Tanya M Laidlaw; Jake J Lee; Jay F Piccirillo; Jayant M Pinto; Lauren T Roland; Robert P Schleimer; Rodney J Schlosser; Julie M Schwaninger; Timothy L Smith; Bruce K Tan; Ming Tan; Elina Toskala; Sally Wenzel; Alkis Togias
Journal:  J Allergy Clin Immunol Pract       Date:  2020-03-04
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