Literature DB >> 33494171

Increased Likelihood of Falling in Older Cannabis Users vs. Non-Users.

Craig D Workman1, Alexandra C Fietsam1, Jacob Sosnoff2, Thorsten Rudroff1,3.   

Abstract

Cannabis is one of the most common drugs in the United States and is the third most prevalent substance consumed by adults aged 50 years and older. Normal aging is associated with physiological changes that make older adults vulnerable to impaired function and geriatric conditions (e.g., falls, cognitive impairment). However, the impact of medical cannabis use on fall risk in older adults remains unexplored. The purpose of this study was to investigate if cannabis use in older adults influences fall risk, cognitive function, and motor function. It was hypothesized that older chronic cannabis users would perform worse than non-users on gait, balance, and cognitive tests. Sixteen older adults, split into cannabis Users and age- and sex-matched Non-Users groups (n = 8/group), participated in the study. The results indicate a higher fall risk, worse one leg standing balance performance, and slower gait speed in Users vs. Non-Users. No significant differences in cognitive function were found. Thus, chronic cannabis use was purported to exacerbate the poorer balance control and slower gait velocity associated with normal aging. Future mechanistic (e.g., neuroimaging) investigations of the short- and long-term effects of using a variety of cannabis products (e.g., THC/CBD ratios, routes of administration) on cognitive function, motor function, and fall incidence in older adults are suggested.

Entities:  

Keywords:  balance; cannabis; fall risk; gait; older adults

Year:  2021        PMID: 33494171      PMCID: PMC7909838          DOI: 10.3390/brainsci11020134

Source DB:  PubMed          Journal:  Brain Sci        ISSN: 2076-3425


  76 in total

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  4 in total

1.  Sample entropy discriminates balance performance of older cannabis users from non-users.

Authors:  Craig D Workman; Jacob J Sosnoff; Thorsten Rudroff
Journal:  Clin Biomech (Bristol, Avon)       Date:  2022-02-04       Impact factor: 2.063

2.  Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study.

Authors:  Nicholas T Vozoris; Jingqin Zhu; Clodagh M Ryan; Chung-Wai Chow; Teresa To
Journal:  BMJ Open Respir Res       Date:  2022-05

3.  Disparity between Perceptual Fall Risk and Physiological Fall Risk in Older Cannabis Users: A Pilot Study.

Authors:  Craig D Workman; Jacob J Sosnoff; Thorsten Rudroff
Journal:  Int J Environ Res Public Health       Date:  2021-12-23       Impact factor: 4.614

4.  Differences in Inhibitory Control and Resting Brain Metabolism between Older Chronic Users of Tetrahydrocannabinol (THC) or Cannabidiol (CBD)-A Pilot Study.

Authors:  Thorsten Rudroff; Craig D Workman; Phillip E Gander; Justin R Deters; Laura L Boles Ponto
Journal:  Brain Sci       Date:  2022-06-23
  4 in total

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