Martin Aguilar1, Jordi Heijman2, Dobromir Dobrev3, Stanley Nattel4. 1. Department of Medicine and Research Centre, Montréal Heart Institute and University of Montréal, Montréal, Québec, Canada. 2. Department of Cardiology, Cardiovascular Research Institute Maastricht, Faculty of Health, Medicine, and Life Sciences, Maastricht University, Maastricht, The Netherlands; Institute of Pharmacology, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany. 3. Department of Medicine and Research Centre, Montréal Heart Institute and University of Montréal, Montréal, Québec, Canada; Institute of Pharmacology, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, Texas, USA. 4. Department of Medicine and Research Centre, Montréal Heart Institute and University of Montréal, Montréal, Québec, Canada; Institute of Pharmacology, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany; L'Institut Hospitalo-Universitaire L'Institut de Rythmologie et Modélisation Cardiaque (IHU LIRYC) and Fondation Bordeaux Université Bordeaux, Bordeaux, France. Electronic address: stanley.nattel@icm-mhi.org.